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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
29.09
Human Site:
Y322
Identified Species:
45.71
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
Y322
A
V
R
T
K
M
V
Y
C
K
I
D
Q
T
Q
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
V334
Q
T
Q
R
K
V
V
V
S
C
S
G
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
F411
K
L
A
S
Y
V
K
F
Y
Q
N
N
K
D
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
Y322
A
V
R
T
K
M
V
Y
C
K
I
D
Q
T
Q
Rat
Rattus norvegicus
XP_215794
451
50894
Y399
A
V
R
T
K
M
V
Y
C
K
I
D
Q
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
Y480
A
V
R
T
K
M
V
Y
S
K
I
D
Q
T
Q
Chicken
Gallus gallus
Q5ZJ64
374
42572
Y322
A
V
K
T
K
M
V
Y
C
K
I
D
Q
T
Q
Frog
Xenopus laevis
Q7ZYU8
374
42287
Y322
A
V
K
T
K
M
V
Y
C
K
I
D
Q
T
Q
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
Y322
A
V
R
T
K
M
V
Y
S
K
I
D
Q
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
R323
V
L
K
T
K
L
V
R
A
R
L
D
Q
A
N
Honey Bee
Apis mellifera
XP_393333
391
44458
R325
V
L
K
T
K
L
V
R
A
R
M
D
Q
A
G
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
S334
A
I
Q
V
N
A
I
S
G
K
I
N
E
M
A
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
K374
V
V
K
S
K
M
A
K
A
K
I
D
Q
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
D350
A
I
A
S
K
I
L
D
C
K
V
D
Q
L
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
E333
V
I
R
S
K
L
V
E
G
R
L
S
Q
K
Q
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
13.3
0
N.A.
N.A.
100
100
N.A.
93.3
93.3
93.3
93.3
N.A.
33.3
33.3
20
53.3
P-Site Similarity:
100
40
46.6
N.A.
N.A.
100
100
N.A.
93.3
100
100
93.3
N.A.
66.6
66.6
53.3
66.6
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
73.3
N.A.
N.A.
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
14
0
0
7
7
0
20
0
0
0
0
14
7
% A
% Cys:
0
0
0
0
0
0
0
0
40
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
74
0
7
0
% D
% Glu:
0
0
0
0
0
0
0
7
0
0
0
0
14
0
7
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
0
0
0
0
14
0
0
7
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
0
0
7
7
0
0
0
60
0
0
0
0
% I
% Lys:
7
0
34
0
87
0
7
7
0
67
0
0
7
7
0
% K
% Leu:
0
20
0
0
0
20
7
0
0
0
14
0
0
20
0
% L
% Met:
0
0
0
0
0
54
0
0
0
0
7
0
0
7
0
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
7
14
0
0
14
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
14
0
0
0
0
0
0
7
0
0
80
0
60
% Q
% Arg:
0
0
40
7
0
0
0
14
0
20
0
0
0
0
0
% R
% Ser:
0
0
0
27
0
0
0
7
20
0
7
7
0
0
0
% S
% Thr:
0
7
0
60
0
0
0
0
0
0
0
0
0
47
0
% T
% Val:
27
54
0
7
0
14
74
7
0
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
47
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _