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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
37.27
Human Site:
S62
Identified Species:
58.57
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
S62
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
S62
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
L75
E
E
G
A
V
F
L
L
L
R
L
K
L
L
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
S62
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Rat
Rattus norvegicus
XP_215794
451
50894
S139
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
S220
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Chicken
Gallus gallus
Q5ZJ64
374
42572
S62
E
D
D
K
D
V
E
S
V
M
N
S
V
V
S
Frog
Xenopus laevis
Q7ZYU8
374
42287
S62
D
D
D
K
D
V
E
S
S
M
N
S
V
V
S
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
S62
D
D
D
K
D
V
E
S
V
M
N
S
I
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
G64
G
E
P
S
Q
I
D
G
I
L
N
S
I
V
S
Honey Bee
Apis mellifera
XP_393333
391
44458
T64
G
N
E
S
E
I
E
T
V
L
N
D
I
V
S
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
L65
S
W
S
Q
D
V
D
L
V
L
N
S
I
S
S
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
T111
E
N
I
D
Q
V
V
T
D
L
D
K
V
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
C81
V
S
D
K
D
L
E
C
V
L
S
V
I
C
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
P63
A
P
E
K
D
F
T
P
A
Y
N
L
L
I
H
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
100
100
86.6
86.6
N.A.
26.6
33.3
40
20
P-Site Similarity:
100
100
40
N.A.
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
66.6
80
66.6
46.6
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
40
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
66.6
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
0
0
0
7
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% C
% Asp:
14
54
60
7
74
0
14
0
7
0
7
7
0
0
0
% D
% Glu:
54
14
14
0
7
0
67
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% F
% Gly:
14
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
7
0
0
14
0
0
7
0
0
0
34
7
0
% I
% Lys:
0
0
0
67
0
0
0
0
0
0
0
14
0
7
7
% K
% Leu:
0
0
0
0
0
7
7
14
7
34
7
7
14
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
54
0
0
0
0
0
% M
% Asn:
0
14
0
0
0
0
0
0
0
0
80
0
0
0
0
% N
% Pro:
0
7
7
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
14
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
7
7
14
0
0
0
54
7
0
7
67
0
7
80
% S
% Thr:
0
0
0
0
0
0
7
14
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
7
67
7
0
67
0
0
7
54
67
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _