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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
34.81
Human Site:
S370
Identified Species:
54.71
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
S370
K
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
S382
K
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
I459
T
M
Q
Q
E
L
Q
I
G
A
D
D
V
E
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
S370
K
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Rat
Rattus norvegicus
XP_215794
451
50894
S447
K
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
S528
Q
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Chicken
Gallus gallus
Q5ZJ64
374
42572
S370
Q
V
K
N
S
L
L
S
L
S
D
T
_
_
_
Frog
Xenopus laevis
Q7ZYU8
374
42287
S370
K
V
K
N
S
L
Y
S
I
S
D
A
_
_
_
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
T370
T
V
K
S
S
L
Q
T
L
S
P
T
A
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
S371
T
V
R
E
G
L
T
S
V
S
S
A
Q
L
D
Honey Bee
Apis mellifera
XP_393333
391
44458
S373
A
V
Q
E
G
M
K
S
V
A
A
A
Q
M
E
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
E382
Q
T
H
N
N
V
H
E
V
N
Q
R
I
E
A
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
S422
T
V
E
G
R
L
E
S
L
Q
Q
Q
M
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
A398
R
A
I
N
T
I
Q
A
N
K
V
T
E
E
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
K381
R
L
V
G
V
V
R
K
A
Q
T
D
V
E
A
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
91.6
91.6
75
53.8
N.A.
26.6
13.3
6.6
26.6
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
100
100
83.3
69.2
N.A.
40
40
46.6
33.3
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
46.6
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
7
7
14
7
20
7
0
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
54
14
0
0
7
% D
% Glu:
0
0
7
14
7
0
7
7
0
0
0
0
7
27
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
14
14
0
0
0
7
0
0
0
0
0
7
% G
% His:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
7
0
7
7
0
0
0
7
0
0
% I
% Lys:
34
0
54
0
0
0
7
7
0
7
0
0
0
0
0
% K
% Leu:
0
7
0
0
0
74
40
0
54
0
0
0
0
14
0
% L
% Met:
0
7
0
0
0
7
0
0
0
0
0
0
7
7
0
% M
% Asn:
0
0
0
60
7
0
0
0
7
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% P
% Gln:
20
0
14
7
0
0
20
0
0
14
14
7
14
0
0
% Q
% Arg:
14
0
7
0
7
0
7
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
0
7
54
0
0
67
0
60
7
0
0
0
0
% S
% Thr:
27
7
0
0
7
0
7
7
0
0
7
54
0
0
0
% T
% Val:
0
74
7
0
7
14
0
0
20
0
7
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
47
54
54
% _