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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
43.33
Human Site:
S337
Identified Species:
68.1
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
S337
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
S349
G
L
G
S
I
C
H
S
T
H
R
T
F
G
K
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
H426
I
D
S
L
G
L
L
H
E
Q
N
M
A
K
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
S337
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Rat
Rattus norvegicus
XP_215794
451
50894
S414
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
S495
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Chicken
Gallus gallus
Q5ZJ64
374
42572
S337
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Frog
Xenopus laevis
Q7ZYU8
374
42287
S337
K
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
S337
R
K
V
V
V
S
H
S
T
H
R
T
F
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
T338
Q
K
V
H
I
S
S
T
M
H
R
T
F
G
A
Honey Bee
Apis mellifera
XP_393333
391
44458
T340
R
K
V
L
I
S
S
T
M
H
R
T
F
G
K
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
Y349
R
T
L
I
V
S
S
Y
Q
H
R
R
F
G
T
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
V389
H
K
V
N
V
S
F
V
T
H
R
T
F
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
H365
Q
T
V
I
V
S
R
H
T
E
R
I
F
G
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
T348
K
V
F
L
V
H
R
T
T
Y
R
V
F
G
E
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
60
0
N.A.
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
53.3
66.6
46.6
66.6
P-Site Similarity:
100
66.6
6.6
N.A.
N.A.
100
100
N.A.
100
100
100
100
N.A.
73.3
86.6
60
73.3
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
46.6
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
N.A.
60
N.A.
N.A.
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
7
% E
% Phe:
0
0
7
0
0
0
7
0
0
0
0
0
94
0
0
% F
% Gly:
7
0
7
0
7
0
0
0
0
0
0
0
0
94
0
% G
% His:
7
0
0
7
0
7
54
14
0
80
0
0
0
0
0
% H
% Ile:
7
0
0
14
20
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
14
67
0
0
0
0
0
0
0
0
0
0
0
7
60
% K
% Leu:
0
7
7
20
0
7
7
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
14
0
0
7
0
0
14
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
14
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% Q
% Arg:
54
0
0
0
0
0
14
0
0
0
94
7
0
0
7
% R
% Ser:
0
0
7
7
0
80
20
54
0
0
0
0
0
0
0
% S
% Thr:
0
14
0
0
0
0
0
20
74
0
0
74
0
0
7
% T
% Val:
0
7
74
47
74
0
0
7
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _