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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF3M
All Species:
29.09
Human Site:
S2
Identified Species:
45.71
UniProt:
Q7L2H7
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L2H7
NP_006351.2
374
42503
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
I
Chimpanzee
Pan troglodytes
XP_001143260
386
43634
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
I
Rhesus Macaque
Macaca mulatta
XP_001084341
492
54740
A6
_
_
M
V
L
L
R
A
L
R
G
Q
V
K
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q99JX4
374
42498
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
I
Rat
Rattus norvegicus
XP_215794
451
50894
S79
R
S
Q
A
F
T
M
S
V
P
A
F
I
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506816
532
60638
S160
R
G
K
G
D
F
E
S
R
V
G
V
G
F
W
Chicken
Gallus gallus
Q5ZJ64
374
42572
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
I
Frog
Xenopus laevis
Q7ZYU8
374
42287
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
V
Zebra Danio
Brachydanio rerio
Q7T3B0
375
42681
S2
_
_
_
_
_
_
M
S
V
P
A
F
I
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7JVI3
387
44068
S3
_
_
_
_
_
M
T
S
H
P
V
F
I
D
L
Honey Bee
Apis mellifera
XP_393333
391
44458
V3
_
_
_
_
_
M
Q
V
P
P
I
F
M
E
L
Nematode Worm
Caenorhab. elegans
Q94261
390
44065
E6
_
_
M
A
D
T
R
E
L
P
V
F
A
Y
I
Sea Urchin
Strong. purpuratus
XP_794675
429
49271
N16
D
L
E
A
V
I
D
N
V
G
V
V
W
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148717
415
46251
V16
E
E
E
P
M
L
A
V
V
R
F
T
A
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEK1
434
49684
F8
M
A
T
P
Q
L
I
F
V
D
G
T
F
A
E
Conservation
Percent
Protein Identity:
100
96.8
68
N.A.
N.A.
99.4
82.7
N.A.
68.2
95.7
88.5
88.5
N.A.
45.7
47.5
30.5
38.2
Protein Similarity:
100
96.8
68
N.A.
N.A.
99.7
82.7
N.A.
69.1
98.1
94.9
95.7
N.A.
66.4
67.5
52.3
54.3
P-Site Identity:
100
100
0
N.A.
N.A.
100
60
N.A.
6.6
100
88.8
100
N.A.
50
20
23
6.6
P-Site Similarity:
100
100
30.7
N.A.
N.A.
100
60
N.A.
20
100
100
100
N.A.
60
50
30.7
26.6
Percent
Protein Identity:
N.A.
26.5
N.A.
N.A.
N.A.
23.5
Protein Similarity:
N.A.
50.3
N.A.
N.A.
N.A.
45.1
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
20
0
0
7
7
0
0
47
0
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
0
14
0
7
0
0
7
0
0
0
54
0
% D
% Glu:
7
7
14
0
0
0
7
7
0
0
0
0
0
14
7
% E
% Phe:
0
0
0
0
7
7
0
7
0
0
7
67
7
7
0
% F
% Gly:
0
7
0
7
0
0
0
0
0
7
20
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
7
0
0
0
7
0
54
0
47
% I
% Lys:
0
0
7
0
0
0
0
0
0
0
0
0
0
14
0
% K
% Leu:
0
7
0
0
7
20
0
0
14
0
0
0
0
0
27
% L
% Met:
7
0
14
0
7
14
47
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
14
0
0
0
0
7
67
0
0
0
0
0
% P
% Gln:
0
0
7
0
7
0
7
0
0
0
0
7
0
0
0
% Q
% Arg:
14
0
0
0
0
0
14
0
7
14
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
0
60
0
0
0
0
0
0
0
% S
% Thr:
0
0
7
0
0
14
7
0
0
0
0
14
0
0
0
% T
% Val:
0
0
0
7
7
0
0
14
67
7
20
14
7
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
67
67
54
54
54
40
0
0
0
0
0
0
0
0
0
% _