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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT6H All Species: 31.52
Human Site: Y272 Identified Species: 53.33
UniProt: Q7KZ85 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7KZ85 NP_003161.2 1726 199073 Y272 R R S I F E M Y E P S E L E S
Chimpanzee Pan troglodytes XP_001142885 1726 199040 Y272 R R S I F E M Y E P S E L E S
Rhesus Macaque Macaca mulatta XP_001106850 1658 190705 Y272 R R S I F E M Y E P S E L E S
Dog Lupus familis XP_537747 1726 199082 Y272 R R S I F E M Y E P S E L E S
Cat Felis silvestris
Mouse Mus musculus Q62383 1726 199067 Y272 R R S I F E M Y E P S E L E S
Rat Rattus norvegicus XP_239258 1726 198998 Y272 R R S I F E M Y E P S E L E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520857 606 68513
Chicken Gallus gallus XP_423183 1642 189299 D187 I D D F I V D D D G Q P L K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q8UVK2 1726 198148 Y261 R R S I F E I Y E P S E L E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W420 1831 208580 Y267 K K T I F D I Y E P S E L K R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34703 1521 175798 A196 D E N L P E G A E D D A R D V
Sea Urchin Strong. purpuratus XP_782276 1326 150573 R35 R K K K R K H R A D Y D E R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23615 1451 168273 E160 F F S E D E E E E E S G L R N
Red Bread Mold Neurospora crassa Q8NIV6 1402 162783 E111 G E A I P E W E R K P Q P Q R
Conservation
Percent
Protein Identity: 100 99.7 96 99.6 N.A. 98 98.3 N.A. 33.6 89.9 N.A. 81.3 N.A. 46 N.A. 34.4 41.7
Protein Similarity: 100 99.8 96 99.8 N.A. 99.1 99.3 N.A. 34.2 93.5 N.A. 90.2 N.A. 65.2 N.A. 53.1 55.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 6.6 N.A. 93.3 N.A. 53.3 N.A. 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 0 20 N.A. 100 N.A. 93.3 N.A. 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.1 25.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.1 43.7
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 40 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 8 8 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 8 8 8 8 8 15 8 8 0 8 0 % D
% Glu: 0 15 0 8 0 72 8 15 72 8 0 58 8 50 0 % E
% Phe: 8 8 0 8 58 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 8 0 0 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 65 8 0 15 0 0 0 0 0 0 0 0 % I
% Lys: 8 15 8 8 0 8 0 0 0 8 0 0 0 15 8 % K
% Leu: 0 0 0 8 0 0 0 0 0 0 0 0 72 0 8 % L
% Met: 0 0 0 0 0 0 43 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 15 0 0 0 0 58 8 8 8 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 0 8 0 % Q
% Arg: 58 50 0 0 8 0 0 8 8 0 0 0 8 15 15 % R
% Ser: 0 0 58 0 0 0 0 0 0 0 65 0 0 0 50 % S
% Thr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 58 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _