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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SUPT6H All Species: 25.76
Human Site: T849 Identified Species: 43.59
UniProt: Q7KZ85 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7KZ85 NP_003161.2 1726 199073 T849 N K K P H V V T V A G E N R D
Chimpanzee Pan troglodytes XP_001142885 1726 199040 T849 N K K P H V V T V A G E N R D
Rhesus Macaque Macaca mulatta XP_001106850 1658 190705 G813 G Q Q L S S I G V E L V D N E
Dog Lupus familis XP_537747 1726 199082 T849 N K K P H V V T V A G E N R D
Cat Felis silvestris
Mouse Mus musculus Q62383 1726 199067 T849 N K K P H V V T I A G E N R D
Rat Rattus norvegicus XP_239258 1726 198998 T849 N K K P H V V T V A G E N R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520857 606 68513
Chicken Gallus gallus XP_423183 1642 189299 T765 N K K P H V V T I A G E N R D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q8UVK2 1726 198148 A840 S K K P H V V A V S G E N R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W420 1831 208580 V853 M K K P H I V V I G A E S R D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34703 1521 175798 L704 D E L Y N T I L E E A K T A V
Sea Urchin Strong. purpuratus XP_782276 1326 150573 R536 R K G N S L V R T L K Q K N Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P23615 1451 168273 S661 S V K L H M S S Q A Q Y I E H
Red Bread Mold Neurospora crassa Q8NIV6 1402 162783 S612 G L I E I K V S L E N D R E F
Conservation
Percent
Protein Identity: 100 99.7 96 99.6 N.A. 98 98.3 N.A. 33.6 89.9 N.A. 81.3 N.A. 46 N.A. 34.4 41.7
Protein Similarity: 100 99.8 96 99.8 N.A. 99.1 99.3 N.A. 34.2 93.5 N.A. 90.2 N.A. 65.2 N.A. 53.1 55.5
P-Site Identity: 100 100 6.6 100 N.A. 93.3 100 N.A. 0 93.3 N.A. 80 N.A. 53.3 N.A. 0 13.3
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. 0 100 N.A. 93.3 N.A. 73.3 N.A. 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.1 25.6
Protein Similarity: N.A. N.A. N.A. N.A. 44.1 43.7
P-Site Identity: N.A. N.A. N.A. N.A. 20 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 50 15 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 0 8 8 0 58 % D
% Glu: 0 8 0 8 0 0 0 0 8 22 0 58 0 15 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 15 0 8 0 0 0 0 8 0 8 50 0 0 0 0 % G
% His: 0 0 0 0 65 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 8 0 8 8 15 0 22 0 0 0 8 0 0 % I
% Lys: 0 65 65 0 0 8 0 0 0 0 8 8 8 0 0 % K
% Leu: 0 8 8 15 0 8 0 8 8 8 8 0 0 0 0 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 43 0 0 8 8 0 0 0 0 0 8 0 50 15 0 % N
% Pro: 0 0 0 58 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 8 0 0 0 0 0 8 0 8 8 0 0 8 % Q
% Arg: 8 0 0 0 0 0 0 8 0 0 0 0 8 58 0 % R
% Ser: 15 0 0 0 15 8 8 15 0 8 0 0 8 0 0 % S
% Thr: 0 0 0 0 0 8 0 43 8 0 0 0 8 0 0 % T
% Val: 0 8 0 0 0 50 72 8 43 0 0 8 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _