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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW1
All Species:
26.97
Human Site:
Y1583
Identified Species:
49.44
UniProt:
Q76N89
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76N89
NP_055867.3
1606
179554
Y1583
N
R
L
D
L
P
P
Y
P
S
Y
S
M
L
Y
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
Y1549
N
R
L
D
L
P
P
Y
P
S
F
S
M
L
Y
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
Y1583
N
R
L
D
L
P
P
Y
P
S
Y
S
M
L
Y
Dog
Lupus familis
XP_850781
1366
151109
P1344
R
L
D
L
P
P
Y
P
S
Y
S
M
L
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4P8
1604
179451
Y1581
N
R
L
D
L
P
P
Y
P
S
Y
S
M
L
Y
Rat
Rattus norvegicus
Q62940
887
102376
S865
L
D
L
P
P
Y
E
S
F
D
E
L
W
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
Y1634
N
R
L
D
L
P
P
Y
P
S
Y
S
M
L
Y
Chicken
Gallus gallus
XP_418870
1586
179204
Y1563
N
R
L
D
L
P
P
Y
P
S
Y
S
M
L
Y
Frog
Xenopus laevis
Q2TAS2
751
86306
E729
R
I
D
I
P
P
Y
E
T
Y
E
K
L
Y
E
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
E743
R
I
D
I
P
P
Y
E
S
Y
D
K
L
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
G985
L
D
L
P
P
Y
E
G
Y
L
Q
L
K
D
K
Honey Bee
Apis mellifera
XP_392900
1204
136801
Y1181
N
R
L
D
L
P
P
Y
P
T
P
E
I
L
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
V787
R
V
D
L
P
Q
Y
V
D
Y
D
S
M
K
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
99.1
75.2
N.A.
88.2
24.9
N.A.
82.1
80.3
23.1
23.4
N.A.
25.1
39
N.A.
N.A.
Protein Similarity:
100
67.8
99.6
78.6
N.A.
92.2
37.8
N.A.
86.9
86.8
33.2
33.6
N.A.
39.4
52.4
N.A.
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
100
6.6
N.A.
100
100
6.6
6.6
N.A.
6.6
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
100
6.6
N.A.
100
100
13.3
13.3
N.A.
6.6
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
31
54
0
0
0
0
8
8
16
0
0
16
8
% D
% Glu:
0
0
0
0
0
0
16
16
0
0
16
8
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
16
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
16
8
8
16
% K
% Leu:
16
8
70
16
54
0
0
0
0
8
0
16
24
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
54
0
0
% M
% Asn:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
16
47
77
54
8
54
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% Q
% Arg:
31
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
16
47
8
54
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
16
31
54
8
31
39
0
0
24
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _