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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW1
All Species:
21.21
Human Site:
T861
Identified Species:
38.89
UniProt:
Q76N89
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76N89
NP_055867.3
1606
179554
T861
T
T
T
W
Q
R
P
T
A
A
A
T
P
D
G
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
T839
T
T
T
W
Q
R
P
T
A
P
P
A
P
Q
V
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
T861
T
T
T
W
Q
R
P
T
A
A
A
T
P
D
G
Dog
Lupus familis
XP_850781
1366
151109
Q668
S
G
N
Q
S
C
E
Q
V
P
G
G
G
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4P8
1604
179451
S858
T
T
T
W
Q
R
P
S
M
A
P
T
P
D
G
Rat
Rattus norvegicus
Q62940
887
102376
P189
F
K
D
F
V
L
H
P
R
S
H
K
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
T909
T
T
T
W
Q
R
P
T
T
A
A
T
P
D
G
Chicken
Gallus gallus
XP_418870
1586
179204
T844
T
T
T
W
Q
R
P
T
A
A
A
T
P
D
G
Frog
Xenopus laevis
Q2TAS2
751
86306
V53
Q
C
H
S
T
D
T
V
K
N
T
L
D
P
K
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
L67
K
W
N
Q
H
Y
D
L
Y
I
G
K
S
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
S309
I
S
V
D
D
T
E
S
G
R
S
A
D
S
I
Honey Bee
Apis mellifera
XP_392900
1204
136801
D505
H
G
R
V
F
Y
I
D
H
I
N
R
T
T
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
E111
T
S
S
G
R
P
R
E
E
T
I
T
R
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
99.1
75.2
N.A.
88.2
24.9
N.A.
82.1
80.3
23.1
23.4
N.A.
25.1
39
N.A.
N.A.
Protein Similarity:
100
67.8
99.6
78.6
N.A.
92.2
37.8
N.A.
86.9
86.8
33.2
33.6
N.A.
39.4
52.4
N.A.
N.A.
P-Site Identity:
100
66.6
100
6.6
N.A.
80
0
N.A.
93.3
100
0
6.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
66.6
100
13.3
N.A.
86.6
13.3
N.A.
93.3
100
0
6.6
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
31
39
31
16
0
0
0
% A
% Cys:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
8
8
8
0
0
0
0
16
54
0
% D
% Glu:
0
0
0
0
0
0
16
8
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
0
8
0
0
0
0
8
0
16
8
8
0
47
% G
% His:
8
0
8
0
8
0
8
0
8
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
16
8
0
0
0
8
% I
% Lys:
8
8
0
0
0
0
0
0
8
0
0
16
0
0
8
% K
% Leu:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
16
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
47
8
0
16
16
0
47
8
0
% P
% Gln:
8
0
0
16
47
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
8
47
8
0
8
8
0
8
8
8
0
% R
% Ser:
8
16
8
8
8
0
0
16
0
8
8
0
16
16
8
% S
% Thr:
54
47
47
0
8
8
8
39
8
8
8
47
8
8
8
% T
% Val:
0
0
8
8
8
0
0
8
8
0
0
0
0
0
16
% V
% Trp:
0
8
0
47
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
16
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _