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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS13
All Species:
3.33
Human Site:
Y677
Identified Species:
18.33
UniProt:
Q76LX8
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76LX8
NP_620594.1
1427
153604
Y677
R
P
D
I
T
F
T
Y
F
Q
P
K
P
R
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118382
1372
146884
L631
C
V
E
A
Q
G
S
L
L
K
T
L
P
P
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q769J6
1426
155338
Y682
H
P
D
I
T
F
S
Y
F
Q
L
K
Q
Q
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415435
942
103552
G254
E
Q
C
K
I
A
F
G
S
V
A
T
A
C
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
G1045
R
V
D
E
S
L
C
G
R
E
Q
K
E
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
74.9
N.A.
N.A.
70.1
N.A.
N.A.
N.A.
36.1
N.A.
N.A.
N.A.
N.A.
N.A.
21.8
N.A.
Protein Similarity:
100
N.A.
78.7
N.A.
N.A.
78.1
N.A.
N.A.
N.A.
48.3
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Identity:
100
N.A.
6.6
N.A.
N.A.
60
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
26.6
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
20
0
0
0
0
20
0
20
20
40
% A
% Cys:
20
0
20
0
0
0
20
0
0
0
0
0
0
20
0
% C
% Asp:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
20
20
0
0
0
0
0
20
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
40
20
0
40
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
20
0
40
0
0
0
0
0
0
0
% G
% His:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
40
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
20
0
0
0
0
0
20
0
60
0
0
0
% K
% Leu:
0
0
0
0
0
20
0
20
20
0
20
20
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
40
0
0
0
0
0
0
0
0
20
0
40
20
0
% P
% Gln:
0
20
0
0
20
0
0
0
0
40
20
0
20
20
20
% Q
% Arg:
40
0
0
0
0
0
0
0
20
0
0
0
0
20
0
% R
% Ser:
0
0
0
0
20
0
40
0
20
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
40
0
20
0
0
0
20
20
0
0
40
% T
% Val:
0
40
0
0
0
0
0
0
0
20
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _