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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASXL2
All Species:
22.73
Human Site:
S1135
Identified Species:
55.56
UniProt:
Q76L83
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76L83
NP_060733.4
1435
153820
S1135
I
S
T
Y
G
R
G
S
E
S
F
R
R
T
H
Chimpanzee
Pan troglodytes
XP_515337
1579
168916
S1279
I
S
T
Y
G
R
G
S
E
S
F
R
R
T
H
Rhesus Macaque
Macaca mulatta
XP_001084149
1435
154080
S1135
I
S
T
Y
G
R
G
S
E
S
F
R
R
T
H
Dog
Lupus familis
XP_853069
2156
231578
K1535
V
S
H
S
A
P
S
K
Q
K
E
F
L
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZ32
1370
147088
T1076
I
S
T
Y
G
R
G
T
E
N
I
K
R
T
H
Rat
Rattus norvegicus
NP_001101481
1000
106175
V719
Q
L
L
Q
G
K
D
V
P
L
E
Q
I
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507684
1473
154520
S1164
I
S
T
Y
G
R
G
S
E
S
L
R
R
A
H
Chicken
Gallus gallus
Q5ZM88
1412
148651
S1114
I
S
T
Y
G
R
G
S
E
S
L
R
R
G
F
Frog
Xenopus laevis
NP_001086579
738
82633
S457
P
E
P
H
P
Q
N
S
E
Q
K
R
K
I
E
Zebra Danio
Brachydanio rerio
XP_001921737
1209
131655
V928
E
S
S
Q
D
Q
S
V
H
L
G
I
F
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.2
96.6
21.7
N.A.
77.4
53.3
N.A.
64.6
58.8
23.4
42.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.5
98.1
36.5
N.A.
83.6
58.4
N.A.
72.8
68.7
34.9
55.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
73.3
6.6
N.A.
86.6
80
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
20
N.A.
86.6
80
40
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
0
0
0
70
0
20
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
30
10
10
0
10
% F
% Gly:
0
0
0
0
70
0
60
0
0
0
10
0
0
20
0
% G
% His:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
50
% H
% Ile:
60
0
0
0
0
0
0
0
0
0
10
10
10
10
0
% I
% Lys:
0
0
0
0
0
10
0
10
0
10
10
10
10
0
0
% K
% Leu:
0
10
10
0
0
0
0
0
0
20
20
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
10
0
10
10
0
0
10
0
0
0
0
0
10
% P
% Gln:
10
0
0
20
0
20
0
0
10
10
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
60
0
0
0
0
0
60
60
0
10
% R
% Ser:
0
80
10
10
0
0
20
60
0
50
0
0
0
0
0
% S
% Thr:
0
0
60
0
0
0
0
10
0
0
0
0
0
40
0
% T
% Val:
10
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _