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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PGAP1 All Species: 20
Human Site: S449 Identified Species: 40
UniProt: Q75T13 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q75T13 NP_079265.2 922 105383 S449 Y V P S V R G S K F V V D C E
Chimpanzee Pan troglodytes XP_001168679 922 105283 S449 Y V P S V H G S K F V V D C E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850469 922 104749 S449 Y V P S V H G S K F V I D C E
Cat Felis silvestris
Mouse Mus musculus Q3UUQ7 922 104531 S449 Y V P S V H G S K F V V D C E
Rat Rattus norvegicus Q765A7 922 104365 S449 Y V P S V H G S K F V V D C E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q66J01 927 105617 F448 P A T N G S K F S V E C E F L
Zebra Danio Brachydanio rerio XP_001922432 1031 115357 P536 L I I D A S N P S G A Q F V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W495 980 111607 T468 D L H N L R K T Y V H W T H L
Honey Bee Apis mellifera XP_001120182 716 81653 S266 N E R M Q A L S Y H F Y H R T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794852 487 54562 G37 Y A T N L E K G K Y T G I P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P43571 1029 117737 S502 I L T V P R S S K D T Q F A A
Red Bread Mold Neurospora crassa Q7SAM0 1256 140105 A680 R L A C N N A A S D V V T L P
Conservation
Percent
Protein Identity: 100 99 N.A. 93 N.A. 90.2 89.8 N.A. N.A. N.A. 53.9 39.3 N.A. 24.6 24.6 N.A. 25
Protein Similarity: 100 99.3 N.A. 96.5 N.A. 95.4 95.2 N.A. N.A. N.A. 70.5 58.8 N.A. 44.1 42.6 N.A. 36.6
P-Site Identity: 100 93.3 N.A. 86.6 N.A. 93.3 93.3 N.A. N.A. N.A. 0 0 N.A. 6.6 6.6 N.A. 13.3
P-Site Similarity: 100 93.3 N.A. 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. 13.3 6.6 N.A. 33.3 6.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 20.2
Protein Similarity: N.A. N.A. N.A. N.A. 40.4 37.7
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 9 0 9 9 9 9 0 0 9 0 0 9 9 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 9 0 42 0 % C
% Asp: 9 0 0 9 0 0 0 0 0 17 0 0 42 0 0 % D
% Glu: 0 9 0 0 0 9 0 0 0 0 9 0 9 0 42 % E
% Phe: 0 0 0 0 0 0 0 9 0 42 9 0 17 9 0 % F
% Gly: 0 0 0 0 9 0 42 9 0 9 0 9 0 0 0 % G
% His: 0 0 9 0 0 34 0 0 0 9 9 0 9 9 0 % H
% Ile: 9 9 9 0 0 0 0 0 0 0 0 9 9 0 9 % I
% Lys: 0 0 0 0 0 0 25 0 59 0 0 0 0 0 0 % K
% Leu: 9 25 0 0 17 0 9 0 0 0 0 0 0 9 17 % L
% Met: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 25 9 9 9 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 42 0 9 0 0 9 0 0 0 0 0 9 9 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 17 0 0 0 % Q
% Arg: 9 0 9 0 0 25 0 0 0 0 0 0 0 9 0 % R
% Ser: 0 0 0 42 0 17 9 59 25 0 0 0 0 0 0 % S
% Thr: 0 0 25 0 0 0 0 9 0 0 17 0 17 0 9 % T
% Val: 0 42 0 9 42 0 0 0 0 17 50 42 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 50 0 0 0 0 0 0 0 17 9 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _