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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS8
All Species:
21.52
Human Site:
T622
Identified Species:
43.03
UniProt:
Q75QN2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75QN2
NP_060334.2
995
113088
T622
M
L
L
L
D
I
H
T
H
E
A
G
T
G
Q
Chimpanzee
Pan troglodytes
XP_519863
1845
206255
T1427
M
L
L
L
D
I
H
T
H
E
A
G
T
G
Q
Rhesus Macaque
Macaca mulatta
XP_001089895
995
113042
T622
M
L
L
L
D
I
H
T
H
E
A
G
T
G
Q
Dog
Lupus familis
XP_544184
955
108586
T582
M
L
L
L
D
I
H
T
H
E
A
G
T
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q80V86
995
113335
T622
M
L
L
L
D
I
R
T
H
E
A
G
V
G
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512811
898
102052
R552
V
R
G
Y
L
E
M
R
L
P
D
I
P
L
R
Chicken
Gallus gallus
NP_001035318
995
112926
T622
M
L
L
L
D
I
Y
T
H
E
A
G
A
G
A
Frog
Xenopus laevis
Q4V847
991
112600
I619
N
E
M
L
L
L
D
I
Y
T
Y
E
A
V
S
Zebra Danio
Brachydanio rerio
NP_001018592
996
113619
H622
L
L
M
E
V
R
A
H
E
E
G
T
A
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611162
1007
113462
H644
L
I
T
W
E
I
L
H
I
Q
I
T
Q
C
L
Honey Bee
Apis mellifera
XP_395965
986
113000
R611
C
L
L
I
E
I
L
R
C
L
H
N
W
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794268
969
109560
A597
Y
V
D
L
L
R
M
A
E
Q
R
G
A
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.4
99.5
94.4
N.A.
95.7
N.A.
N.A.
84.1
89.4
80.5
69.9
N.A.
24.8
31.2
N.A.
30.1
Protein Similarity:
100
53.1
100
95.6
N.A.
98.6
N.A.
N.A.
87.9
95.1
90.6
82.5
N.A.
46.9
51.6
N.A.
50.9
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
0
80
6.6
13.3
N.A.
6.6
20
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
13.3
86.6
26.6
26.6
N.A.
33.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
9
0
0
50
0
34
0
9
% A
% Cys:
9
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% C
% Asp:
0
0
9
0
50
0
9
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
9
17
9
0
0
17
59
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
9
59
0
50
9
% G
% His:
0
0
0
0
0
0
34
17
50
0
9
0
0
0
0
% H
% Ile:
0
9
0
9
0
67
0
9
9
0
9
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% K
% Leu:
17
67
59
67
25
9
17
0
9
9
0
0
0
9
9
% L
% Met:
50
0
17
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
42
% Q
% Arg:
0
9
0
0
0
17
9
17
0
0
9
0
0
0
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
0
9
0
0
0
0
50
0
9
0
17
34
0
17
% T
% Val:
9
9
0
0
9
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
9
0
0
9
0
0
9
0
9
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _