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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INTS8 All Species: 33.33
Human Site: S640 Identified Species: 66.67
UniProt: Q75QN2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q75QN2 NP_060334.2 995 113088 S640 R P P S D L I S R V R G Y L E
Chimpanzee Pan troglodytes XP_519863 1845 206255 S1445 R P P S D L I S R V R G Y L E
Rhesus Macaque Macaca mulatta XP_001089895 995 113042 S640 R P P S D L I S R V R G Y L E
Dog Lupus familis XP_544184 955 108586 S600 R P P S D L I S R V R G Y L E
Cat Felis silvestris
Mouse Mus musculus Q80V86 995 113335 S640 R P P S D L I S R V R G Y L E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512811 898 102052 M570 A E E C V A F M L N W R E N E
Chicken Gallus gallus NP_001035318 995 112926 S640 R P P S D L I S R V R G Y L E
Frog Xenopus laevis Q4V847 991 112600 S637 R P P P E L I S R V R G Y L E
Zebra Danio Brachydanio rerio NP_001018592 996 113619 S640 R P P P D L V S R V R G Y L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611162 1007 113462 Q662 H Q K P L D L Q S L G G R C K
Honey Bee Apis mellifera XP_395965 986 113000 T629 C D T E N L I T R C K Q C L G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794268 969 109560 A615 D F K Q M V L A C L L G T R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.4 99.5 94.4 N.A. 95.7 N.A. N.A. 84.1 89.4 80.5 69.9 N.A. 24.8 31.2 N.A. 30.1
Protein Similarity: 100 53.1 100 95.6 N.A. 98.6 N.A. N.A. 87.9 95.1 90.6 82.5 N.A. 46.9 51.6 N.A. 50.9
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 100 86.6 86.6 N.A. 6.6 26.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 6.6 100 93.3 93.3 N.A. 26.6 46.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 9 0 0 0 0 0 0 0 % A
% Cys: 9 0 0 9 0 0 0 0 9 9 0 0 9 9 0 % C
% Asp: 9 9 0 0 59 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 9 9 9 0 0 0 0 0 0 0 9 0 75 % E
% Phe: 0 9 0 0 0 0 9 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 9 84 0 0 9 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 67 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 17 0 0 0 0 0 0 0 9 0 0 0 9 % K
% Leu: 0 0 0 0 9 75 17 0 9 17 9 0 0 75 0 % L
% Met: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 0 0 0 9 0 % N
% Pro: 0 67 67 25 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 0 9 0 0 0 9 0 0 0 9 0 0 0 % Q
% Arg: 67 0 0 0 0 0 0 0 75 0 67 9 9 9 0 % R
% Ser: 0 0 0 50 0 0 0 67 9 0 0 0 0 0 9 % S
% Thr: 0 0 9 0 0 0 0 9 0 0 0 0 9 0 0 % T
% Val: 0 0 0 0 9 9 9 0 0 67 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _