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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS8
All Species:
15.76
Human Site:
S327
Identified Species:
31.52
UniProt:
Q75QN2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75QN2
NP_060334.2
995
113088
S327
S
Q
Q
L
T
P
Y
S
Q
V
H
I
C
L
R
Chimpanzee
Pan troglodytes
XP_519863
1845
206255
S1132
S
Q
Q
L
T
P
Y
S
Q
V
H
I
C
L
R
Rhesus Macaque
Macaca mulatta
XP_001089895
995
113042
S327
S
Q
Q
L
T
P
Y
S
Q
V
H
I
C
L
R
Dog
Lupus familis
XP_544184
955
108586
Y298
I
C
L
R
S
G
N
Y
Q
D
V
V
K
I
F
Cat
Felis silvestris
Mouse
Mus musculus
Q80V86
995
113335
S327
S
Q
Q
L
T
P
Y
S
Q
V
H
I
C
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512811
898
102052
T292
F
K
V
C
A
C
N
T
V
C
D
V
L
E
G
Chicken
Gallus gallus
NP_001035318
995
112926
N327
S
Q
Q
T
T
P
Y
N
Q
I
H
N
C
M
K
Frog
Xenopus laevis
Q4V847
991
112600
Q327
Q
P
A
T
P
Y
S
Q
I
H
N
F
M
K
T
Zebra Danio
Brachydanio rerio
NP_001018592
996
113619
G327
E
S
Q
H
T
P
Y
G
Q
I
S
C
F
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611162
1007
113462
R375
I
L
R
M
D
N
R
R
R
E
I
P
F
I
S
Honey Bee
Apis mellifera
XP_395965
986
113000
C295
L
D
G
C
C
L
A
C
E
V
S
I
E
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794268
969
109560
N303
A
L
I
G
Q
N
L
N
R
L
P
S
N
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.4
99.5
94.4
N.A.
95.7
N.A.
N.A.
84.1
89.4
80.5
69.9
N.A.
24.8
31.2
N.A.
30.1
Protein Similarity:
100
53.1
100
95.6
N.A.
98.6
N.A.
N.A.
87.9
95.1
90.6
82.5
N.A.
46.9
51.6
N.A.
50.9
P-Site Identity:
100
100
100
6.6
N.A.
100
N.A.
N.A.
0
60
0
40
N.A.
0
13.3
N.A.
0
P-Site Similarity:
100
100
100
26.6
N.A.
100
N.A.
N.A.
20
86.6
6.6
53.3
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% A
% Cys:
0
9
0
17
9
9
0
9
0
9
0
9
42
0
0
% C
% Asp:
0
9
0
0
9
0
0
0
0
9
9
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
9
9
0
0
9
17
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
9
17
0
9
% F
% Gly:
0
0
9
9
0
9
0
9
0
0
0
0
0
9
9
% G
% His:
0
0
0
9
0
0
0
0
0
9
42
0
0
0
0
% H
% Ile:
17
0
9
0
0
0
0
0
9
17
9
42
0
17
9
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
9
% K
% Leu:
9
17
9
34
0
9
9
0
0
9
0
0
9
34
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
9
17
0
% M
% Asn:
0
0
0
0
0
17
17
17
0
0
9
9
9
0
0
% N
% Pro:
0
9
0
0
9
50
0
0
0
0
9
9
0
0
9
% P
% Gln:
9
42
50
0
9
0
0
9
59
0
0
0
0
0
0
% Q
% Arg:
0
0
9
9
0
0
9
9
17
0
0
0
0
0
42
% R
% Ser:
42
9
0
0
9
0
9
34
0
0
17
9
0
0
9
% S
% Thr:
0
0
0
17
50
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
9
0
0
0
0
0
9
42
9
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
50
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _