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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS8
All Species:
16.06
Human Site:
S316
Identified Species:
32.12
UniProt:
Q75QN2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75QN2
NP_060334.2
995
113088
S316
C
D
V
L
V
P
S
S
D
S
T
S
Q
Q
L
Chimpanzee
Pan troglodytes
XP_519863
1845
206255
S1121
C
D
V
L
V
P
S
S
D
S
T
S
Q
Q
L
Rhesus Macaque
Macaca mulatta
XP_001089895
995
113042
S316
C
D
V
L
V
P
S
S
D
S
T
S
Q
Q
L
Dog
Lupus familis
XP_544184
955
108586
S287
S
Q
Q
L
T
P
Y
S
Q
V
H
I
C
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80V86
995
113335
S316
C
D
V
L
V
P
S
S
D
N
N
S
Q
Q
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512811
898
102052
D281
Q
Q
G
N
E
A
L
D
E
I
C
F
K
V
C
Chicken
Gallus gallus
NP_001035318
995
112926
D316
C
G
V
L
T
S
S
D
D
D
A
S
Q
Q
T
Frog
Xenopus laevis
Q4V847
991
112600
N316
C
G
V
L
A
P
S
N
V
V
S
Q
P
A
T
Zebra Danio
Brachydanio rerio
NP_001018592
996
113619
S316
C
R
T
L
T
G
T
S
D
L
N
E
S
Q
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611162
1007
113462
D364
S
L
L
N
N
Y
T
D
I
V
S
I
L
R
M
Honey Bee
Apis mellifera
XP_395965
986
113000
K284
K
R
H
I
I
Q
A
K
E
L
I
L
D
G
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794268
969
109560
A292
S
K
L
E
G
Y
L
A
A
C
S
A
L
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.4
99.5
94.4
N.A.
95.7
N.A.
N.A.
84.1
89.4
80.5
69.9
N.A.
24.8
31.2
N.A.
30.1
Protein Similarity:
100
53.1
100
95.6
N.A.
98.6
N.A.
N.A.
87.9
95.1
90.6
82.5
N.A.
46.9
51.6
N.A.
50.9
P-Site Identity:
100
100
100
20
N.A.
86.6
N.A.
N.A.
0
53.3
33.3
33.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
93.3
N.A.
N.A.
13.3
53.3
46.6
40
N.A.
33.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
9
9
9
0
9
9
0
9
0
% A
% Cys:
59
0
0
0
0
0
0
0
0
9
9
0
9
0
17
% C
% Asp:
0
34
0
0
0
0
0
25
50
9
0
0
9
0
0
% D
% Glu:
0
0
0
9
9
0
0
0
17
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
17
9
0
9
9
0
0
0
0
0
0
0
9
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
0
0
9
9
0
0
0
9
9
9
17
0
9
0
% I
% Lys:
9
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% K
% Leu:
0
9
17
67
0
0
17
0
0
17
0
9
17
9
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
17
9
0
0
9
0
9
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
50
0
0
0
0
0
0
9
0
0
% P
% Gln:
9
17
9
0
0
9
0
0
9
0
0
9
42
50
0
% Q
% Arg:
0
17
0
0
0
0
0
0
0
0
0
0
0
9
9
% R
% Ser:
25
0
0
0
0
9
50
50
0
25
25
42
9
0
0
% S
% Thr:
0
0
9
0
25
0
17
0
0
0
25
0
0
0
17
% T
% Val:
0
0
50
0
34
0
0
0
9
25
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _