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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A5 All Species: 17.88
Human Site: S31 Identified Species: 30.26
UniProt: Q71RS6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71RS6 NP_995322.1 500 54888 S31 H L P L S G T S L P Q R L P R
Chimpanzee Pan troglodytes XP_510380 500 54850 S31 H L P L S G T S L P Q R L P R
Rhesus Macaque Macaca mulatta XP_001112601 500 55038 S31 R L P V P G A S L P Q R L P R
Dog Lupus familis XP_851849 501 55168 S31 H L P P P G A S L L Q R V P R
Cat Felis silvestris
Mouse Mus musculus Q8C261 501 54965 S31 Y L P V R G V S L P P R L P R
Rat Rattus norvegicus Q9EPQ0 624 69371 D53 R K L M Q V N D T L T S E D A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517974 336 36438
Chicken Gallus gallus Q9IAL7 651 72677 D99 Q N E G S T P D S P T S M K H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 S43 A G L S F Q G S S S A R V R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN12 642 70657 P87 Q A S T Q S T P I H G A V P T
Honey Bee Apis mellifera XP_624828 470 51842 K28 P H D L F D E K Q R Q G G A V
Nematode Worm Caenorhab. elegans P34315 590 66151 T62 I Q A G W N S T Q V C E Y V K
Sea Urchin Strong. purpuratus XP_780438 570 63240 Y61 T S S P G M D Y F T D F T S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJI2 643 70138 Y101 G L H K H M G Y A D Q C E F L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.8 90.4 N.A. 84.6 34.7 N.A. 46.7 31.6 N.A. 66.4 N.A. 34.7 37.2 23.2 37.7
Protein Similarity: 100 99.5 96.4 94.8 N.A. 92.2 51.9 N.A. 55.4 48.6 N.A. 81.2 N.A. 51.5 59.2 40.5 55.9
P-Site Identity: 100 100 73.3 66.6 N.A. 66.6 0 N.A. 0 13.3 N.A. 20 N.A. 13.3 13.3 0 0
P-Site Similarity: 100 100 80 73.3 N.A. 80 6.6 N.A. 0 20 N.A. 26.6 N.A. 26.6 13.3 20 0
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 15 0 8 0 8 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % C
% Asp: 0 0 8 0 0 8 8 15 0 8 8 0 0 8 0 % D
% Glu: 0 0 8 0 0 0 8 0 0 0 0 8 15 0 0 % E
% Phe: 0 0 0 0 15 0 0 0 8 0 0 8 0 8 0 % F
% Gly: 8 8 0 15 8 36 15 0 0 0 8 8 8 0 8 % G
% His: 22 8 8 0 8 0 0 0 0 8 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 8 0 8 0 0 0 8 0 0 0 0 0 8 8 % K
% Leu: 0 43 15 22 0 0 0 0 36 15 0 0 29 0 8 % L
% Met: 0 0 0 8 0 15 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 0 0 8 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 0 36 15 15 0 8 8 0 36 8 0 0 43 0 % P
% Gln: 15 8 0 0 15 8 0 0 15 0 43 0 0 0 0 % Q
% Arg: 15 0 0 0 8 0 0 0 0 8 0 43 0 8 43 % R
% Ser: 0 8 15 8 22 8 8 43 15 8 0 15 0 8 0 % S
% Thr: 8 0 0 8 0 8 22 8 8 8 15 0 8 0 8 % T
% Val: 0 0 0 15 0 8 8 0 0 8 0 0 22 8 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 15 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _