KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP50
All Species:
19.09
Human Site:
S259
Identified Species:
52.5
UniProt:
Q70EL3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70EL3
NP_987090.1
339
38955
S259
Q
E
T
A
V
R
A
S
I
S
K
A
P
K
I
Chimpanzee
Pan troglodytes
XP_001175420
436
49795
E317
R
D
S
L
K
K
I
E
I
W
K
L
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001107612
223
25435
S149
R
R
S
H
E
K
G
S
A
Q
R
C
C
R
K
Dog
Lupus familis
XP_862693
384
43707
S263
Q
E
T
A
V
R
A
S
I
S
K
A
P
K
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6P8X6
390
44525
T253
Q
E
A
A
V
R
T
T
I
S
K
V
P
K
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506997
556
61458
T437
Q
D
A
A
V
R
A
T
V
V
K
A
P
N
V
Chicken
Gallus gallus
O57429
357
40913
F270
R
A
S
K
L
T
T
F
V
N
F
P
L
K
D
Frog
Xenopus laevis
Q6GNI6
523
60030
T395
Q
E
S
T
K
Q
L
T
M
K
K
L
P
I
V
Zebra Danio
Brachydanio rerio
A6H8I0
506
58102
T378
Q
E
S
T
K
Q
L
T
M
K
R
L
P
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30
57.2
71.8
N.A.
66.6
N.A.
N.A.
35
29.9
21.6
20.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.2
59.8
78.1
N.A.
73
N.A.
N.A.
46.2
46.5
34.9
35.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
6.6
100
N.A.
73.3
N.A.
N.A.
53.3
6.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
53.3
40
100
N.A.
80
N.A.
N.A.
80
40
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
23
45
0
0
34
0
12
0
0
34
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
12
0
0
% C
% Asp:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
56
0
0
12
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
45
0
0
0
0
23
34
% I
% Lys:
0
0
0
12
34
23
0
0
0
23
67
0
0
45
12
% K
% Leu:
0
0
0
12
12
0
23
0
0
0
0
34
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
78
12
0
% P
% Gln:
67
0
0
0
0
23
0
0
0
12
0
0
0
0
0
% Q
% Arg:
34
12
0
0
0
45
0
0
0
0
23
0
0
12
0
% R
% Ser:
0
0
56
0
0
0
0
34
0
34
0
0
0
0
0
% S
% Thr:
0
0
23
23
0
12
23
45
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
45
0
0
0
23
12
0
12
0
0
45
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _