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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RAPH1
All Species:
1.52
Human Site:
S610
Identified Species:
3.7
UniProt:
Q70E73
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q70E73
NP_976241.1
1250
135256
S610
T
S
L
V
P
P
L
S
P
Q
P
K
I
V
T
Chimpanzee
Pan troglodytes
XP_516044
1252
135697
A610
P
S
S
S
L
T
H
A
F
S
M
S
F
K
I
Rhesus Macaque
Macaca mulatta
XP_001101993
662
72668
L52
Y
S
V
G
F
K
D
L
N
E
S
L
N
A
L
Dog
Lupus familis
XP_545607
979
108307
T369
L
D
W
S
L
V
E
T
I
S
E
L
Q
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5A3
670
74301
E60
N
E
S
L
N
A
L
E
D
Q
D
L
D
A
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509550
268
31003
Chicken
Gallus gallus
Q5ZL23
485
54730
Frog
Xenopus laevis
Q6DCV1
653
72662
V43
T
T
E
I
N
F
S
V
G
F
K
D
L
N
E
Zebra Danio
Brachydanio rerio
Q6PFT9
646
70983
T36
A
P
L
A
K
P
P
T
I
P
E
P
Q
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797256
1407
155923
Q571
Q
E
A
E
T
H
H
Q
L
S
M
H
R
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
31.3
70.5
N.A.
31
N.A.
N.A.
20.3
23.8
30.4
32.2
N.A.
N.A.
N.A.
N.A.
26.1
Protein Similarity:
100
97.9
40.1
72
N.A.
40
N.A.
N.A.
20.9
30.7
39.1
40.9
N.A.
N.A.
N.A.
N.A.
42.1
P-Site Identity:
100
6.6
6.6
0
N.A.
13.3
N.A.
N.A.
0
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
13.3
20
13.3
N.A.
20
N.A.
N.A.
0
0
26.6
20
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
10
0
10
0
0
0
0
0
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
10
0
10
0
10
10
10
0
0
% D
% Glu:
0
20
10
10
0
0
10
10
0
10
20
0
0
20
20
% E
% Phe:
0
0
0
0
10
10
0
0
10
10
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
20
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
20
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
10
10
0
0
0
0
10
10
0
10
0
% K
% Leu:
10
0
20
10
20
0
20
10
10
0
0
30
10
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
0
0
10
10
% M
% Asn:
10
0
0
0
20
0
0
0
10
0
0
0
10
10
0
% N
% Pro:
10
10
0
0
10
20
10
0
10
10
10
10
0
0
10
% P
% Gln:
10
0
0
0
0
0
0
10
0
20
0
0
20
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
30
20
20
0
0
10
10
0
30
10
10
0
0
0
% S
% Thr:
20
10
0
0
10
10
0
20
0
0
0
0
0
0
10
% T
% Val:
0
0
10
10
0
10
0
10
0
0
0
0
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _