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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC3
All Species:
10
Human Site:
T883
Identified Species:
24.44
UniProt:
Q6ZXV5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZXV5
NP_861448.2
915
104009
T883
G
K
N
G
D
E
E
T
P
H
K
T
T
K
D
Chimpanzee
Pan troglodytes
XP_522486
914
103832
T882
G
K
N
G
D
E
E
T
P
H
K
T
T
K
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532644
915
103928
T883
G
K
N
T
D
K
Q
T
P
H
K
T
T
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH0
920
104179
D887
S
T
E
N
A
D
Q
D
A
P
H
K
T
T
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCD5
836
94386
L822
T
Q
S
N
L
R
K
L
W
N
I
M
E
K
Q
Zebra Danio
Brachydanio rerio
XP_001922486
906
102514
I882
K
S
K
S
T
K
E
I
K
D
I
E
K
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
L913
Y
D
P
L
E
F
K
L
P
Q
D
R
P
T
H
Honey Bee
Apis mellifera
XP_393964
996
112258
S883
G
K
T
D
S
V
F
S
N
H
H
N
H
I
G
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
K678
V
A
K
Q
N
L
Q
K
L
E
E
H
N
C
Y
Sea Urchin
Strong. purpuratus
XP_797370
844
95271
R828
L
R
Q
K
I
K
E
R
S
T
A
K
Q
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
93.8
N.A.
89.7
N.A.
N.A.
N.A.
N.A.
26
73
N.A.
51.2
47.9
28.2
47.3
Protein Similarity:
100
99.7
N.A.
97.1
N.A.
94.6
N.A.
N.A.
N.A.
N.A.
43.2
85.9
N.A.
66.7
63.9
45.2
65.6
P-Site Identity:
100
100
N.A.
73.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
13.3
N.A.
6.6
20
0
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
20
N.A.
20
26.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
0
10
30
10
0
10
0
10
10
0
0
0
20
% D
% Glu:
0
0
10
0
10
20
40
0
0
10
10
10
10
10
10
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
40
0
0
20
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
40
20
10
10
0
10
% H
% Ile:
0
0
0
0
10
0
0
10
0
0
20
0
0
10
0
% I
% Lys:
10
40
20
10
0
30
20
10
10
0
30
20
10
50
20
% K
% Leu:
10
0
0
10
10
10
0
20
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
30
20
10
0
0
0
10
10
0
10
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
40
10
0
0
10
0
0
% P
% Gln:
0
10
10
10
0
0
30
0
0
10
0
0
10
0
10
% Q
% Arg:
0
10
0
0
0
10
0
10
0
0
0
10
0
0
10
% R
% Ser:
10
10
10
10
10
0
0
10
10
0
0
0
0
0
0
% S
% Thr:
10
10
10
10
10
0
0
30
0
10
0
30
40
20
0
% T
% Val:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _