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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMTC3
All Species:
9.39
Human Site:
S822
Identified Species:
22.96
UniProt:
Q6ZXV5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZXV5
NP_861448.2
915
104009
S822
V
R
D
K
I
S
S
S
S
F
I
E
P
I
F
Chimpanzee
Pan troglodytes
XP_522486
914
103832
S821
V
R
D
K
I
S
S
S
S
F
I
E
P
I
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532644
915
103928
S822
R
D
K
I
S
S
S
S
F
A
E
Q
P
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRH0
920
104179
S826
V
R
D
R
I
S
S
S
G
I
V
E
Q
P
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DCD5
836
94386
N761
M
L
R
Q
A
S
L
N
E
E
A
E
K
F
Y
Zebra Danio
Brachydanio rerio
XP_001922486
906
102514
M821
V
R
N
K
M
A
A
M
S
A
A
G
Q
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K4B6
926
105342
R852
L
C
V
V
F
V
E
R
K
R
L
A
K
A
A
Honey Bee
Apis mellifera
XP_393964
996
112258
L822
V
K
A
R
I
S
R
L
S
P
E
Q
R
D
T
Nematode Worm
Caenorhab. elegans
Q20144
690
77719
N617
S
C
H
A
K
H
S
N
F
T
A
A
E
N
H
Sea Urchin
Strong. purpuratus
XP_797370
844
95271
F767
V
I
K
S
Q
Q
L
F
Q
R
I
V
D
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
93.8
N.A.
89.7
N.A.
N.A.
N.A.
N.A.
26
73
N.A.
51.2
47.9
28.2
47.3
Protein Similarity:
100
99.7
N.A.
97.1
N.A.
94.6
N.A.
N.A.
N.A.
N.A.
43.2
85.9
N.A.
66.7
63.9
45.2
65.6
P-Site Identity:
100
100
N.A.
26.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
13.3
26.6
N.A.
0
26.6
6.6
13.3
P-Site Similarity:
100
100
N.A.
40
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
40
53.3
N.A.
13.3
46.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
10
10
0
0
20
30
20
0
10
10
% A
% Cys:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
30
0
0
0
0
0
0
0
0
0
10
10
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
10
20
40
10
0
10
% E
% Phe:
0
0
0
0
10
0
0
10
20
20
0
0
0
10
20
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% G
% His:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
10
40
0
0
0
0
10
30
0
0
20
10
% I
% Lys:
0
10
20
30
10
0
0
0
10
0
0
0
20
0
0
% K
% Leu:
10
10
0
0
0
0
20
10
0
0
10
0
0
10
10
% L
% Met:
10
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
20
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
30
20
0
% P
% Gln:
0
0
0
10
10
10
0
0
10
0
0
20
20
0
0
% Q
% Arg:
10
40
10
20
0
0
10
10
0
20
0
0
10
0
0
% R
% Ser:
10
0
0
10
10
60
50
40
40
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% T
% Val:
60
0
10
10
0
10
0
0
0
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _