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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TOM1L2
All Species:
35.76
Human Site:
S226
Identified Species:
87.41
UniProt:
Q6ZVM7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZVM7
NP_001028723.1
507
55556
S226
E
Q
I
A
R
L
R
S
E
L
D
V
V
R
G
Chimpanzee
Pan troglodytes
XP_001155008
493
53712
S222
E
Q
I
G
K
L
R
S
E
L
E
M
V
S
G
Rhesus Macaque
Macaca mulatta
XP_001091844
507
55541
S226
E
Q
I
A
R
L
R
S
E
L
D
V
V
R
G
Dog
Lupus familis
XP_546659
508
55648
S227
E
Q
I
A
R
L
R
S
E
L
D
V
V
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5SRX1
507
55644
S226
E
Q
I
A
R
L
R
S
E
L
D
I
V
R
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510686
562
61633
S281
E
Q
I
A
R
L
R
S
E
L
D
V
V
R
G
Chicken
Gallus gallus
O12940
515
57006
S222
E
Q
I
K
K
L
R
S
E
L
E
V
V
N
G
Frog
Xenopus laevis
Q68FJ8
507
55834
S228
E
Q
I
G
R
L
R
S
E
L
D
I
V
R
G
Zebra Danio
Brachydanio rerio
XP_688819
510
56155
S229
E
Q
I
C
K
L
R
S
E
L
D
I
V
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
Y302
E
P
A
N
S
T
Q
Y
K
P
D
K
Q
S
T
Conservation
Percent
Protein Identity:
100
58.5
99.6
98
N.A.
94.8
N.A.
N.A.
67.6
60.5
82.4
71.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.3
99.8
98.2
N.A.
97.8
N.A.
N.A.
73.3
73.1
88.5
82.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
93.3
N.A.
N.A.
100
73.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
N.A.
N.A.
100
86.6
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
50
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% D
% Glu:
100
0
0
0
0
0
0
0
90
0
20
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
90
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
90
0
0
0
0
0
0
0
0
30
0
0
0
% I
% Lys:
0
0
0
10
30
0
0
0
10
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
0
90
0
0
0
90
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
90
0
0
0
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
60
0
90
0
0
0
0
0
0
70
0
% R
% Ser:
0
0
0
0
10
0
0
90
0
0
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
50
90
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _