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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C14orf145
All Species:
20
Human Site:
S740
Identified Species:
44
UniProt:
Q6ZU80
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZU80
NP_689659.2
1094
128015
S740
I
R
T
L
K
A
E
S
L
E
E
K
N
M
A
Chimpanzee
Pan troglodytes
XP_522919
1094
128092
S740
I
R
T
L
K
A
E
S
L
E
E
K
N
M
A
Rhesus Macaque
Macaca mulatta
XP_001104541
1092
127884
S741
I
R
T
L
K
A
E
S
L
E
E
K
N
M
A
Dog
Lupus familis
XP_547936
1314
152397
S951
I
R
T
L
K
A
E
S
I
E
D
K
N
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BI22
1102
128485
S739
I
R
M
L
K
A
E
S
L
E
D
K
N
M
A
Rat
Rattus norvegicus
P02563
1938
223490
S1543
V
E
K
L
E
L
Q
S
A
L
E
E
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42184
1433
161009
N1049
L
K
A
A
Q
K
K
N
D
E
L
E
T
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001083005
969
112677
K664
S
L
T
Q
L
L
R
K
Y
H
I
L
R
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
R1524
T
I
E
L
E
A
Q
R
T
K
V
L
E
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P12844
1969
225491
G1530
K
D
L
T
D
Q
L
G
E
G
G
R
S
V
A
Sea Urchin
Strong. purpuratus
XP_790106
952
111519
N647
I
A
E
E
E
K
Q
N
I
K
Q
D
L
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
95.8
71
N.A.
78.1
21.2
N.A.
N.A.
21.2
N.A.
36.6
N.A.
20.8
N.A.
20.7
25.2
Protein Similarity:
100
99.2
97.2
77.5
N.A.
87.7
36.2
N.A.
N.A.
41.1
N.A.
58
N.A.
35.5
N.A.
36.3
47.9
P-Site Identity:
100
100
100
80
N.A.
86.6
26.6
N.A.
N.A.
13.3
N.A.
6.6
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
53.3
N.A.
N.A.
53.3
N.A.
6.6
N.A.
40
N.A.
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
55
0
0
10
0
0
0
10
0
73
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
10
0
19
10
0
0
0
% D
% Glu:
0
10
19
10
28
0
46
0
10
55
37
19
10
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
55
10
0
0
0
0
0
0
19
0
10
0
0
0
0
% I
% Lys:
10
10
10
0
46
19
10
10
0
19
0
46
0
19
10
% K
% Leu:
10
10
10
64
10
19
10
0
37
10
10
19
10
10
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
37
0
% M
% Asn:
0
0
0
0
0
0
0
19
0
0
0
0
46
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
10
28
0
0
0
10
0
0
10
0
% Q
% Arg:
0
46
0
0
0
0
10
10
0
0
0
10
10
0
0
% R
% Ser:
10
0
0
0
0
0
0
55
0
0
0
0
10
0
0
% S
% Thr:
10
0
46
10
0
0
0
0
10
0
0
0
10
10
0
% T
% Val:
10
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _