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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C14orf145 All Species: 20.3
Human Site: S489 Identified Species: 44.67
UniProt: Q6ZU80 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZU80 NP_689659.2 1094 128015 S489 L K L K A Q E S I R Q W K L K
Chimpanzee Pan troglodytes XP_522919 1094 128092 S489 L K L K A Q E S I R Q W K L K
Rhesus Macaque Macaca mulatta XP_001104541 1092 127884 S490 L K L K A Q E S I R Q W K L K
Dog Lupus familis XP_547936 1314 152397 S700 L K L K A Q E S I R Q W K L K
Cat Felis silvestris
Mouse Mus musculus Q8BI22 1102 128485 S488 L K A K A Q E S I R Q W K L K
Rat Rattus norvegicus P02563 1938 223490 T1128 E E L E A E R T A R A K V E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O42184 1433 161009 V656 L K T Q M E K V K L D Y E N E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001083005 969 112677 Q439 Q T E R T R R Q L A D A L G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q99323 2057 236625 A1170 D E M Q A Q L A K R E E E L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P12844 1969 225491 A1129 K E L T A R N A E L E E E L E
Sea Urchin Strong. purpuratus XP_790106 952 111519 E422 D Q L Q D L E E R R R V K S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 95.8 71 N.A. 78.1 21.2 N.A. N.A. 21.2 N.A. 36.6 N.A. 20.8 N.A. 20.7 25.2
Protein Similarity: 100 99.2 97.2 77.5 N.A. 87.7 36.2 N.A. N.A. 41.1 N.A. 58 N.A. 35.5 N.A. 36.3 47.9
P-Site Identity: 100 100 100 100 N.A. 93.3 26.6 N.A. N.A. 13.3 N.A. 0 N.A. 26.6 N.A. 20 26.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 53.3 N.A. N.A. 53.3 N.A. 20 N.A. 66.6 N.A. 60 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 73 0 0 19 10 10 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 19 0 0 0 10 0 0 0 0 0 19 0 0 0 0 % D
% Glu: 10 28 10 10 0 19 55 10 10 0 19 19 28 10 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 46 0 0 0 0 0 0 % I
% Lys: 10 55 0 46 0 0 10 0 19 0 0 10 55 0 55 % K
% Leu: 55 0 64 0 0 10 10 0 10 19 0 0 10 64 0 % L
% Met: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 10 0 28 0 55 0 10 0 0 46 0 0 0 0 % Q
% Arg: 0 0 0 10 0 19 19 0 10 73 10 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 46 0 0 0 0 0 10 19 % S
% Thr: 0 10 10 10 10 0 0 10 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 46 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _