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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC108
All Species:
11.21
Human Site:
S425
Identified Species:
30.83
UniProt:
Q6ZU64
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZU64
NP_919278.2
1925
217250
S425
P
G
E
K
K
C
V
S
V
F
F
H
P
K
T
Chimpanzee
Pan troglodytes
XP_526033
1925
217136
S425
P
G
E
K
K
C
V
S
V
F
F
H
P
K
T
Rhesus Macaque
Macaca mulatta
XP_001096641
1925
217889
S424
P
G
E
K
K
C
V
S
V
F
F
H
P
K
T
Dog
Lupus familis
XP_545652
1897
214402
A401
L
G
Q
T
S
E
Q
A
L
W
I
E
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3V0B4
1847
209116
W399
H
S
C
V
N
F
H
W
V
K
L
G
E
R
R
Rat
Rattus norvegicus
XP_002730094
1840
208047
T399
L
G
E
H
P
E
Q
T
L
W
I
E
N
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422054
1830
203536
Q414
T
P
T
G
C
L
Q
Q
T
V
L
K
M
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663368
1796
201685
D413
A
H
Y
Q
F
D
M
D
T
G
G
H
S
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790343
1891
211121
H399
Q
C
G
K
V
E
P
H
T
T
Q
T
L
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
95.4
75.5
N.A.
69.5
69.8
N.A.
N.A.
42.1
N.A.
34.2
N.A.
N.A.
N.A.
N.A.
35
Protein Similarity:
100
99
97.8
83.8
N.A.
80.4
81.2
N.A.
N.A.
58.4
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
52.6
P-Site Identity:
100
100
100
6.6
N.A.
6.6
13.3
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
46.6
N.A.
13.3
46.6
N.A.
N.A.
0
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
12
12
0
12
34
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
45
0
0
34
0
0
0
0
0
23
12
0
0
% E
% Phe:
0
0
0
0
12
12
0
0
0
34
34
0
0
0
12
% F
% Gly:
0
56
12
12
0
0
0
0
0
12
12
12
12
0
12
% G
% His:
12
12
0
12
0
0
12
12
0
0
0
45
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
23
0
0
12
0
% I
% Lys:
0
0
0
45
34
0
0
0
0
12
0
12
0
34
0
% K
% Leu:
23
0
0
0
0
12
0
0
23
0
23
0
12
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
34
12
0
0
12
0
12
0
0
0
0
0
34
0
0
% P
% Gln:
12
0
12
12
0
0
34
12
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
12
% R
% Ser:
0
12
0
0
12
0
0
34
0
0
0
0
12
0
23
% S
% Thr:
12
0
12
12
0
0
0
12
34
12
0
12
0
0
34
% T
% Val:
0
0
0
12
12
0
34
0
45
12
0
0
0
23
12
% V
% Trp:
0
0
0
0
0
0
0
12
0
23
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _