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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC108 All Species: 14.85
Human Site: S1735 Identified Species: 40.83
UniProt: Q6ZU64 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZU64 NP_919278.2 1925 217250 S1735 M P I L P V P S S S W E D G K
Chimpanzee Pan troglodytes XP_526033 1925 217136 S1735 M P I L P V P S S S W E D G K
Rhesus Macaque Macaca mulatta XP_001096641 1925 217889 S1734 M P I L P L P S S S W E D G K
Dog Lupus familis XP_545652 1897 214402 S1648 A P V L S P S S S S W E A S K
Cat Felis silvestris
Mouse Mus musculus Q3V0B4 1847 209116 P1666 V P I L S L P P S Y E G R K S
Rat Rattus norvegicus XP_002730094 1840 208047 S1654 V P I L S L P S S F E V G K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422054 1830 203536 P1698 V R R S L Q E P I P Y F S Q F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663368 1796 201685 S1658 Q P H S S S D S Q D H V Q M S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790343 1891 211121 Q1684 L P P S Q A A Q R H E A M E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 95.4 75.5 N.A. 69.5 69.8 N.A. N.A. 42.1 N.A. 34.2 N.A. N.A. N.A. N.A. 35
Protein Similarity: 100 99 97.8 83.8 N.A. 80.4 81.2 N.A. N.A. 58.4 N.A. 52.6 N.A. N.A. N.A. N.A. 52.6
P-Site Identity: 100 100 93.3 53.3 N.A. 33.3 40 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 60 N.A. 46.6 53.3 N.A. N.A. 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 12 12 0 0 0 0 12 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 12 0 0 12 0 0 34 0 0 % D
% Glu: 0 0 0 0 0 0 12 0 0 0 34 45 0 12 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 12 0 12 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 12 12 34 0 % G
% His: 0 0 12 0 0 0 0 0 0 12 12 0 0 0 0 % H
% Ile: 0 0 56 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 23 45 % K
% Leu: 12 0 0 67 12 34 0 0 0 0 0 0 0 0 0 % L
% Met: 34 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 89 12 0 34 12 56 23 0 12 0 0 0 0 0 % P
% Gln: 12 0 0 0 12 12 0 12 12 0 0 0 12 12 0 % Q
% Arg: 0 12 12 0 0 0 0 0 12 0 0 0 12 0 0 % R
% Ser: 0 0 0 34 45 12 12 67 67 45 0 0 12 12 45 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 34 0 12 0 0 23 0 0 0 0 0 23 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 45 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 12 12 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _