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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC108 All Species: 17.58
Human Site: S1118 Identified Species: 48.33
UniProt: Q6ZU64 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZU64 NP_919278.2 1925 217250 S1118 L D V S S M G S A E G I T R K
Chimpanzee Pan troglodytes XP_526033 1925 217136 S1118 L D V S S M G S A E G I T R K
Rhesus Macaque Macaca mulatta XP_001096641 1925 217889 S1117 L D V S S M G S A E G I T R K
Dog Lupus familis XP_545652 1897 214402 S1047 K H L W H L F S L D R L N S Y
Cat Felis silvestris
Mouse Mus musculus Q3V0B4 1847 209116 S1050 L D I C S M G S T E G I T R K
Rat Rattus norvegicus XP_002730094 1840 208047 G1043 S S M G S A E G L T R K H L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_422054 1830 203536 S1087 A A A C S A G S A S G I S R L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002663368 1796 201685 S1063 L R R D P S P S E L T F R V P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790343 1891 211121 A1044 A R C Y G S A A G I S K A R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 95.4 75.5 N.A. 69.5 69.8 N.A. N.A. 42.1 N.A. 34.2 N.A. N.A. N.A. N.A. 35
Protein Similarity: 100 99 97.8 83.8 N.A. 80.4 81.2 N.A. N.A. 58.4 N.A. 52.6 N.A. N.A. N.A. N.A. 52.6
P-Site Identity: 100 100 100 6.6 N.A. 80 6.6 N.A. N.A. 46.6 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 86.6 13.3 N.A. N.A. 53.3 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 12 12 0 0 23 12 12 45 0 0 0 12 0 0 % A
% Cys: 0 0 12 23 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 45 0 12 0 0 0 0 0 12 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 12 0 12 45 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 12 12 0 56 12 12 0 56 0 0 0 0 % G
% His: 0 12 0 0 12 0 0 0 0 0 0 0 12 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 12 0 56 0 0 0 % I
% Lys: 12 0 0 0 0 0 0 0 0 0 0 23 0 0 45 % K
% Leu: 56 0 12 0 0 12 0 0 23 12 0 12 0 12 23 % L
% Met: 0 0 12 0 0 45 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % N
% Pro: 0 0 0 0 12 0 12 0 0 0 0 0 0 0 12 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 23 12 0 0 0 0 0 0 0 23 0 12 67 0 % R
% Ser: 12 12 0 34 67 23 0 78 0 12 12 0 12 12 0 % S
% Thr: 0 0 0 0 0 0 0 0 12 12 12 0 45 0 0 % T
% Val: 0 0 34 0 0 0 0 0 0 0 0 0 0 12 0 % V
% Trp: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _