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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN12
All Species:
3.64
Human Site:
S468
Identified Species:
8
UniProt:
Q6ZSI9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.8
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZSI9
NP_653292.2
719
81037
S468
G
L
W
D
S
P
R
S
H
A
L
L
P
R
L
Chimpanzee
Pan troglodytes
XP_001169048
714
81876
R462
Q
P
A
V
H
L
K
R
D
F
F
L
A
N
A
Rhesus Macaque
Macaca mulatta
XP_001114134
714
81832
R462
Q
P
A
L
H
L
K
R
D
F
F
L
A
N
A
Dog
Lupus familis
XP_541639
525
59144
R287
R
L
R
N
P
W
G
R
V
E
W
T
G
A
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER56
720
80570
S469
D
L
W
D
S
P
R
S
R
A
L
L
P
G
L
Rat
Rattus norvegicus
Q78EJ9
703
79537
R452
H
T
D
A
H
L
G
R
D
F
F
L
G
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513498
700
79649
K450
Q
T
N
I
H
L
N
K
N
F
F
L
T
N
K
Chicken
Gallus gallus
P00789
705
80333
K453
S
Q
N
V
H
L
K
K
D
F
F
L
R
N
Q
Frog
Xenopus laevis
NP_001080485
713
80989
R461
Q
S
G
V
H
L
K
R
D
F
F
L
Q
N
A
Zebra Danio
Brachydanio rerio
XP_689397
704
80421
R452
R
V
G
V
H
L
K
R
D
F
F
L
K
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VT65
925
103795
L664
M
Q
V
K
P
Q
G
L
N
F
F
K
Y
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
43.8
66.3
N.A.
86.1
42.7
N.A.
40.3
43.2
42.1
42.9
N.A.
31.1
N.A.
N.A.
N.A.
Protein Similarity:
100
60.7
61
68.4
N.A.
91.3
59.3
N.A.
58
59.2
59.9
58.8
N.A.
45.5
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
80
13.3
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
13.3
N.A.
80
13.3
N.A.
13.3
13.3
13.3
20
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
0
0
0
0
0
19
0
0
19
10
37
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
19
0
0
0
0
55
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
73
73
0
0
0
0
% F
% Gly:
10
0
19
0
0
0
28
0
0
0
0
0
19
10
0
% G
% His:
10
0
0
0
64
0
0
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
46
19
0
0
0
10
10
0
10
% K
% Leu:
0
28
0
10
0
64
0
10
0
0
19
82
0
0
19
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
19
10
0
0
10
0
19
0
0
0
0
46
0
% N
% Pro:
0
19
0
0
19
19
0
0
0
0
0
0
19
0
0
% P
% Gln:
37
19
0
0
0
10
0
0
0
0
0
0
10
0
19
% Q
% Arg:
19
0
10
0
0
0
19
55
10
0
0
0
10
28
0
% R
% Ser:
10
10
0
0
19
0
0
19
0
0
0
0
0
0
0
% S
% Thr:
0
19
0
0
0
0
0
0
0
0
0
10
10
0
10
% T
% Val:
0
10
10
37
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
19
0
0
10
0
0
0
0
10
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _