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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GK5
All Species:
25.15
Human Site:
S252
Identified Species:
46.11
UniProt:
Q6ZS86
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZS86
NP_001034636.1
529
59168
S252
L
P
P
V
R
D
T
S
H
N
F
G
S
V
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112337
529
58933
S252
L
P
P
V
R
D
T
S
H
N
F
G
S
V
D
Dog
Lupus familis
XP_542815
534
59669
S257
L
P
P
V
K
D
T
S
H
N
F
G
S
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX05
534
59794
S257
L
P
P
V
K
D
T
S
Y
N
F
G
S
V
D
Rat
Rattus norvegicus
XP_001069076
635
69671
S358
L
P
P
V
R
D
T
S
Y
N
F
G
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509239
618
68864
G231
N
H
P
Q
Q
T
V
G
G
F
Y
P
L
I
G
Chicken
Gallus gallus
Q5ZMJ4
517
57242
S247
Y
P
P
V
K
D
T
S
F
N
F
G
S
A
D
Frog
Xenopus laevis
Q6GP95
479
52009
L226
L
M
C
W
S
S
F
L
C
S
L
L
S
I
P
Zebra Danio
Brachydanio rerio
A0JPE9
510
56468
S227
L
P
K
V
Q
D
T
S
H
K
F
G
L
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647763
556
62043
P264
G
I
N
S
K
I
L
P
R
V
V
D
N
G
Y
Honey Bee
Apis mellifera
XP_392521
512
57267
N235
Q
V
V
E
T
S
G
N
F
G
S
T
P
K
D
Nematode Worm
Caenorhab. elegans
NP_001024503
523
58507
N242
L
F
P
I
V
D
S
N
L
K
D
M
N
K
L
Sea Urchin
Strong. purpuratus
XP_787253
475
52657
Q223
I
N
A
V
V
G
D
Q
Q
A
A
L
F
G
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.7
83.9
N.A.
80.5
68.8
N.A.
33.8
61.6
59.9
61
N.A.
38.4
44.6
36.6
43.4
Protein Similarity:
100
N.A.
97.9
90
N.A.
88.3
75.4
N.A.
44.9
78.4
72.2
75
N.A.
57.3
63.5
56.5
61
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
93.3
N.A.
6.6
73.3
13.3
66.6
N.A.
0
6.6
20
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
80
26.6
73.3
N.A.
13.3
13.3
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
8
8
0
0
8
0
% A
% Cys:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
62
8
0
0
0
8
8
0
0
62
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
8
0
16
8
54
0
8
0
0
% F
% Gly:
8
0
0
0
0
8
8
8
8
8
0
54
0
16
8
% G
% His:
0
8
0
0
0
0
0
0
31
0
0
0
0
0
0
% H
% Ile:
8
8
0
8
0
8
0
0
0
0
0
0
0
16
0
% I
% Lys:
0
0
8
0
31
0
0
0
0
16
0
0
0
16
0
% K
% Leu:
62
0
0
0
0
0
8
8
8
0
8
16
16
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
8
8
0
0
0
0
16
0
47
0
0
16
0
0
% N
% Pro:
0
54
62
0
0
0
0
8
0
0
0
8
8
0
8
% P
% Gln:
8
0
0
8
16
0
0
8
8
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
24
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
16
8
54
0
8
8
0
54
0
0
% S
% Thr:
0
0
0
0
8
8
54
0
0
0
0
8
0
0
0
% T
% Val:
0
8
8
62
16
0
8
0
0
8
8
0
0
39
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
16
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _