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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF574
All Species:
12.12
Human Site:
S453
Identified Species:
44.44
UniProt:
Q6ZN55
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN55
NP_073589.4
896
98900
S453
E
A
P
E
P
P
V
S
E
E
T
S
A
G
P
Chimpanzee
Pan troglodytes
A2T759
682
76399
R291
Q
S
H
H
S
S
E
R
P
Y
T
C
T
E
C
Rhesus Macaque
Macaca mulatta
XP_001104279
896
98904
S453
E
A
P
E
P
P
V
S
E
E
T
S
A
G
P
Dog
Lupus familis
XP_541593
914
100556
T472
E
A
P
E
P
P
V
T
E
E
G
P
G
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BY46
900
99442
C456
E
A
P
E
L
P
V
C
E
E
S
S
A
E
P
Rat
Rattus norvegicus
Q504L7
898
99336
S454
E
A
P
E
L
P
V
S
E
E
S
S
A
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694427
997
111125
D576
S
E
G
G
G
V
E
D
K
R
M
V
P
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.1
99.3
93
N.A.
93.6
93.9
N.A.
N.A.
N.A.
N.A.
31.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
39.9
99.4
94.1
N.A.
95.8
96
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
73.3
80
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
80
N.A.
80
86.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
72
0
0
0
0
0
0
0
0
0
0
58
15
15
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
15
0
0
15
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
72
15
0
72
0
0
29
0
72
72
0
0
0
43
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
15
15
0
0
0
0
0
15
0
15
43
0
% G
% His:
0
0
15
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
72
0
43
72
0
0
15
0
0
15
15
0
72
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
15
0
15
0
0
0
0
0
% R
% Ser:
15
15
0
0
15
15
0
43
0
0
29
58
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
43
0
15
0
0
% T
% Val:
0
0
0
0
0
15
72
0
0
0
0
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _