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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UNC5A
All Species:
22.12
Human Site:
Y560
Identified Species:
54.07
UniProt:
Q6ZN44
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN44
NP_588610.2
842
92932
Y560
E
A
P
S
H
L
Y
Y
C
Q
L
E
A
S
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093654
943
103349
Y661
E
A
P
S
H
L
Y
Y
C
Q
L
E
A
S
A
Dog
Lupus familis
XP_865859
842
93010
Y560
E
A
P
S
H
L
Y
Y
C
Q
L
E
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1S4
898
98839
Y616
E
S
P
S
H
L
Y
Y
C
Q
L
E
A
G
A
Rat
Rattus norvegicus
O08721
898
98822
Y616
E
S
P
S
H
L
Y
Y
C
Q
L
E
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515238
648
71003
R392
L
S
S
Q
T
Y
F
R
S
L
P
R
G
A
S
Chicken
Gallus gallus
Q7T2Z5
931
102888
Y649
E
N
F
T
T
P
C
Y
I
Q
L
D
P
E
A
Frog
Xenopus laevis
Q8JGT4
943
105065
Y661
E
T
L
N
T
P
C
Y
C
Q
L
E
S
H
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95TU8
1072
116399
F778
E
T
I
N
T
P
M
F
V
Q
L
E
A
T
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q26261
919
101607
F626
E
N
L
N
T
N
M
F
V
Q
F
E
Q
P
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.2
96.9
N.A.
90.6
89.8
N.A.
48.3
51.2
48.9
N.A.
N.A.
25.2
N.A.
22.9
N.A.
Protein Similarity:
100
N.A.
88.1
98
N.A.
92.6
91.7
N.A.
55.8
67.2
66
N.A.
N.A.
42.1
N.A.
38.5
N.A.
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
86.6
N.A.
0
33.3
40
N.A.
N.A.
33.3
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
26.6
46.6
60
N.A.
N.A.
53.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
30
0
0
0
0
0
0
0
0
0
0
60
10
60
% A
% Cys:
0
0
0
0
0
0
20
0
60
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
90
0
0
0
0
0
0
0
0
0
0
80
0
10
0
% E
% Phe:
0
0
10
0
0
0
10
20
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
30
10
% G
% His:
0
0
0
0
50
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
20
0
0
50
0
0
0
10
80
0
0
0
0
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% M
% Asn:
0
20
0
30
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
50
0
0
30
0
0
0
0
10
0
10
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
90
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
30
10
50
0
0
0
0
10
0
0
0
10
20
20
% S
% Thr:
0
20
0
10
50
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
20
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
50
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _