Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC5A All Species: 16.36
Human Site: S232 Identified Species: 40
UniProt: Q6ZN44 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6ZN44 NP_588610.2 842 92932 S232 N I V A R R R S A S A A V I V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093654 943 103349 K333 C E G Q N V Q K T A C A T L C
Dog Lupus familis XP_865859 842 93010 S232 N I V A R R R S A S A A V I V
Cat Felis silvestris
Mouse Mus musculus Q8K1S4 898 98839 K288 C E G Q N V Q K T A C A T L C
Rat Rattus norvegicus O08721 898 98822 K288 C E G Q N V Q K T A C A T L C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515238 648 71003 P71 L E E G I V L P C R P P E G V
Chicken Gallus gallus Q7T2Z5 931 102888 S250 N I V A K R K S T T A T V I V
Frog Xenopus laevis Q8JGT4 943 105065 S239 N I V A K R R S T T A T V I V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95TU8 1072 116399 S314 N I A G R R V S D S A V L I V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q26261 919 101607 T264 C K G E E E M T R S C K V P C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.2 96.9 N.A. 90.6 89.8 N.A. 48.3 51.2 48.9 N.A. N.A. 25.2 N.A. 22.9 N.A.
Protein Similarity: 100 N.A. 88.1 98 N.A. 92.6 91.7 N.A. 55.8 67.2 66 N.A. N.A. 42.1 N.A. 38.5 N.A.
P-Site Identity: 100 N.A. 6.6 100 N.A. 6.6 6.6 N.A. 6.6 66.6 73.3 N.A. N.A. 60 N.A. 13.3 N.A.
P-Site Similarity: 100 N.A. 26.6 100 N.A. 26.6 26.6 N.A. 6.6 86.6 86.6 N.A. N.A. 66.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 40 0 0 0 0 20 30 50 50 0 0 0 % A
% Cys: 40 0 0 0 0 0 0 0 10 0 40 0 0 0 40 % C
% Asp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % D
% Glu: 0 40 10 10 10 10 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 40 20 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 50 0 0 10 0 0 0 0 0 0 0 0 50 0 % I
% Lys: 0 10 0 0 20 0 10 30 0 0 0 10 0 0 0 % K
% Leu: 10 0 0 0 0 0 10 0 0 0 0 0 10 30 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 0 30 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 10 10 0 10 0 % P
% Gln: 0 0 0 30 0 0 30 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 30 50 30 0 10 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 40 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 10 50 20 0 20 30 0 0 % T
% Val: 0 0 40 0 0 40 10 0 0 0 0 10 50 0 60 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _