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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K15
All Species:
13.64
Human Site:
T171
Identified Species:
37.5
UniProt:
Q6ZN16
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN16
NP_001001671.2
1313
147437
T171
L
S
L
K
D
M
V
T
Q
K
N
T
A
S
S
Chimpanzee
Pan troglodytes
XP_001171211
1375
154924
C201
Q
S
L
K
E
I
I
C
Q
K
N
T
M
C
T
Rhesus Macaque
Macaca mulatta
XP_001111127
1297
143635
F164
Q
A
L
R
E
D
V
F
Q
K
N
S
D
C
V
Dog
Lupus familis
XP_548885
1422
158482
T267
L
S
L
K
D
M
V
T
Q
K
N
T
A
S
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AQW0
1331
149309
T175
L
S
L
K
D
M
V
T
Q
K
N
T
A
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514080
1407
157705
T257
L
T
L
K
D
M
V
T
Q
K
N
T
A
S
S
Chicken
Gallus gallus
XP_419725
1260
143069
L146
L
V
D
R
F
I
Q
L
L
K
V
A
Q
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001155222
1364
153160
C187
Q
S
L
Q
D
L
I
C
Q
K
N
M
T
C
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202919
1288
145042
L153
L
C
E
E
D
S
A
L
C
P
L
L
T
D
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
44.2
81.6
N.A.
86
N.A.
N.A.
70.8
57.3
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
45.4
Protein Similarity:
100
72.6
60.9
86.4
N.A.
90.3
N.A.
N.A.
79.4
73.5
N.A.
71.5
N.A.
N.A.
N.A.
N.A.
62.2
P-Site Identity:
100
46.6
33.3
100
N.A.
100
N.A.
N.A.
93.3
20
N.A.
40
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
73.3
60
100
N.A.
100
N.A.
N.A.
100
40
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
0
12
0
0
0
0
12
45
12
12
% A
% Cys:
0
12
0
0
0
0
0
23
12
0
0
0
0
34
0
% C
% Asp:
0
0
12
0
67
12
0
0
0
0
0
0
12
12
0
% D
% Glu:
0
0
12
12
23
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
23
23
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
56
0
0
0
0
0
89
0
0
0
0
0
% K
% Leu:
67
0
78
0
0
12
0
23
12
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
45
0
0
0
0
0
12
12
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% P
% Gln:
34
0
0
12
0
0
12
0
78
0
0
0
12
0
0
% Q
% Arg:
0
0
0
23
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
0
56
0
0
0
12
0
0
0
0
0
12
0
45
56
% S
% Thr:
0
12
0
0
0
0
0
45
0
0
0
56
23
0
12
% T
% Val:
0
12
0
0
0
0
56
0
0
0
12
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _