KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EML6
All Species:
31.21
Human Site:
Y422
Identified Species:
85.83
UniProt:
Q6ZMW3
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMW3
NP_001034842.2
1958
217899
Y422
K
F
S
P
D
G
S
Y
L
A
V
G
S
N
D
Chimpanzee
Pan troglodytes
XP_510110
1978
220219
Y422
K
Y
S
P
D
G
T
Y
L
A
V
G
C
N
D
Rhesus Macaque
Macaca mulatta
XP_001112056
2003
222288
Y429
K
F
S
P
D
G
S
Y
L
A
V
G
S
N
D
Dog
Lupus familis
XP_538494
2109
233569
Y422
K
F
S
P
D
G
S
Y
L
A
V
G
S
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5SQM0
1958
217923
Y422
K
F
S
P
D
G
S
Y
L
A
V
G
S
N
D
Rat
Rattus norvegicus
Q6ED65
1977
219789
Y422
K
Y
S
P
D
G
T
Y
L
A
V
G
C
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509974
1966
218306
Y422
K
F
S
P
D
G
S
Y
L
A
V
G
S
N
D
Chicken
Gallus gallus
XP_421310
1977
220113
F422
K
Y
S
P
D
G
N
F
L
A
V
G
S
N
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919110
1948
216353
Y422
K
F
S
P
D
G
S
Y
L
A
V
G
S
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
92.7
89.4
N.A.
97
74
N.A.
95.2
75
N.A.
82.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.5
94
91.2
N.A.
98.9
86.4
N.A.
98.3
87.3
N.A.
91.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
80
N.A.
100
80
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
23
0
0
% C
% Asp:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
67
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
100
0
0
0
0
0
100
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
100
0
% N
% Pro:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
100
0
0
0
67
0
0
0
0
0
78
0
0
% S
% Thr:
0
0
0
0
0
0
23
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
34
0
0
0
0
0
89
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _