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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THSD4
All Species:
14.55
Human Site:
S394
Identified Species:
35.56
UniProt:
Q6ZMP0
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMP0
NP_079093.2
1018
112450
S394
G
C
D
D
Y
L
G
S
D
K
V
V
D
K
C
Chimpanzee
Pan troglodytes
XP_523113
1017
112376
S393
G
C
D
D
Y
L
G
S
D
K
V
V
D
K
C
Rhesus Macaque
Macaca mulatta
XP_001089233
695
77390
A114
V
V
E
I
P
Q
G
A
T
K
I
N
I
T
E
Dog
Lupus familis
XP_544753
731
81639
T151
V
E
I
P
Q
G
A
T
K
I
N
I
T
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q3UTY6
1018
113224
S394
G
C
D
D
F
L
G
S
D
K
V
L
D
K
C
Rat
Rattus norvegicus
Q4FZU4
1030
112766
E372
Y
Q
W
E
P
F
T
E
V
Q
G
S
Q
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_413780
1008
112452
S395
G
C
D
D
Y
L
G
S
D
K
V
I
D
K
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684575
641
70986
G61
C
G
V
C
A
G
D
G
S
S
C
E
L
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392121
710
77519
F130
E
L
R
H
S
S
N
F
L
A
L
R
D
G
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001182864
608
67786
I28
Q
D
C
P
E
G
A
I
D
F
R
L
E
Q
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
67.5
64.2
N.A.
87.9
39.1
N.A.
N.A.
73.7
N.A.
34.7
N.A.
N.A.
22.2
N.A.
23.4
Protein Similarity:
100
99.5
68
67.4
N.A.
91.8
53.5
N.A.
N.A.
82.9
N.A.
45
N.A.
N.A.
35.4
N.A.
34.3
P-Site Identity:
100
100
13.3
0
N.A.
86.6
6.6
N.A.
N.A.
93.3
N.A.
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
33.3
20
N.A.
100
26.6
N.A.
N.A.
100
N.A.
0
N.A.
N.A.
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
20
10
0
10
0
0
0
0
0
% A
% Cys:
10
40
10
10
0
0
0
0
0
0
10
0
0
0
60
% C
% Asp:
0
10
40
40
0
0
10
0
50
0
0
0
50
0
0
% D
% Glu:
10
10
10
10
10
0
0
10
0
0
0
10
10
10
10
% E
% Phe:
0
0
0
0
10
10
0
10
0
10
0
0
0
10
0
% F
% Gly:
40
10
0
0
0
30
50
10
0
0
10
0
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
10
0
10
10
20
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
50
0
0
0
40
0
% K
% Leu:
0
10
0
0
0
40
0
0
10
0
10
20
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
10
10
0
0
20
% N
% Pro:
0
0
0
20
20
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
0
10
10
0
0
0
10
0
0
10
10
0
% Q
% Arg:
0
0
10
0
0
0
0
0
0
0
10
10
0
10
0
% R
% Ser:
0
0
0
0
10
10
0
40
10
10
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
10
10
0
0
0
10
10
0
% T
% Val:
20
10
10
0
0
0
0
0
10
0
40
20
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
30
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _