KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL34
All Species:
9.09
Human Site:
S221
Identified Species:
28.57
UniProt:
Q6ZMJ4
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZMJ4
NP_689669.1
242
27482
S221
P
P
P
P
W
S
P
S
S
P
P
H
S
T
G
Chimpanzee
Pan troglodytes
XP_511082
242
27492
S221
P
P
P
P
W
S
P
S
S
P
P
H
S
T
G
Rhesus Macaque
Macaca mulatta
XP_001107090
242
27544
S221
P
P
P
P
W
S
P
S
S
P
P
H
S
T
G
Dog
Lupus familis
XP_853152
428
47210
I413
P
L
S
Q
S
P
P
I
S
L
P
R
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1R4
235
26746
N211
L
M
Q
C
T
A
T
N
V
Y
P
L
S
R
Q
Rat
Rattus norvegicus
Q4KM46
234
26754
P219
Y
P
L
P
R
Q
P
P
T
S
L
P
R
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506705
616
65864
R374
L
Q
S
L
P
P
A
R
P
A
S
L
R
V
D
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122173
213
25492
Y198
F
T
K
E
D
D
N
Y
D
Y
C
E
V
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.1
43.2
N.A.
68.5
68.1
N.A.
20.2
N.A.
N.A.
23.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
95.8
48.3
N.A.
79.3
78
N.A.
29.3
N.A.
N.A.
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
33.3
N.A.
13.3
20
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
26.6
33.3
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
13
13
0
0
13
0
0
0
0
0
% A
% Cys:
0
0
0
13
0
0
0
0
0
0
13
0
0
0
0
% C
% Asp:
0
0
0
0
13
13
0
0
13
0
0
0
0
0
13
% D
% Glu:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
38
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
25
13
13
13
0
0
0
0
0
13
13
25
0
0
0
% L
% Met:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
13
0
0
0
0
0
0
13
% N
% Pro:
50
50
38
50
13
25
63
13
13
38
63
13
0
13
13
% P
% Gln:
0
13
13
13
0
13
0
0
0
0
0
0
0
0
13
% Q
% Arg:
0
0
0
0
13
0
0
13
0
0
0
13
25
13
13
% R
% Ser:
0
0
25
0
13
38
0
38
50
13
13
0
63
13
0
% S
% Thr:
0
13
0
0
13
0
13
0
13
0
0
0
0
38
0
% T
% Val:
0
0
0
0
0
0
0
0
13
0
0
0
13
13
0
% V
% Trp:
0
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
13
0
25
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _