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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPSR1
All Species:
9.7
Human Site:
Y244
Identified Species:
17.78
UniProt:
Q6W5P4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6W5P4
NP_997055.1
371
42687
Y244
I
W
I
K
S
K
T
Y
E
T
V
I
S
N
C
Chimpanzee
Pan troglodytes
XP_001168820
371
42711
Y244
I
W
I
K
S
K
T
Y
E
T
V
I
S
N
C
Rhesus Macaque
Macaca mulatta
Q56H79
371
42612
Y244
I
W
I
K
S
K
T
Y
E
T
V
I
S
N
C
Dog
Lupus familis
XP_539511
374
42921
H247
I
W
I
K
S
K
A
H
E
T
V
I
S
N
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZP8
371
42420
H244
I
W
M
K
S
K
T
H
E
T
V
I
S
N
C
Rat
Rattus norvegicus
P0C0L6
372
42620
H245
I
W
I
K
S
K
A
H
E
T
V
I
S
N
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519137
132
15251
Chicken
Gallus gallus
XP_426022
373
42686
A245
W
M
K
S
K
A
Q
A
V
I
V
S
S
C
T
Frog
Xenopus laevis
P70031
453
51139
E270
L
Y
R
G
I
Q
F
E
M
D
L
N
K
E
A
Zebra Danio
Brachydanio rerio
XP_001341507
388
44497
I243
K
T
K
R
D
Q
C
I
T
L
T
P
K
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868T3
506
55785
V319
W
A
K
G
S
I
F
V
P
T
E
R
A
G
F
Honey Bee
Apis mellifera
XP_001122652
353
39441
V227
V
K
M
T
L
V
I
V
F
V
F
I
L
C
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784373
461
51252
T250
V
W
R
N
M
G
K
T
P
D
S
D
R
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97
88.2
N.A.
89.2
88.9
N.A.
31
73.9
22.5
30.4
N.A.
31.6
35
N.A.
27.5
Protein Similarity:
100
99.4
98.6
93.8
N.A.
94.3
94.6
N.A.
34.5
86.3
40.4
50
N.A.
47.8
54.4
N.A.
45.1
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
0
13.3
0
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
0
13.3
26.6
13.3
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
16
8
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
16
47
% C
% Asp:
0
0
0
0
8
0
0
0
0
16
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
47
0
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
16
0
8
0
8
0
0
0
8
% F
% Gly:
0
0
0
16
0
8
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
24
0
0
0
0
0
0
0
% H
% Ile:
47
0
39
0
8
8
8
8
0
8
0
54
0
0
0
% I
% Lys:
8
8
24
47
8
47
8
0
0
0
0
0
16
8
8
% K
% Leu:
8
0
0
0
8
0
0
0
0
8
8
0
8
0
0
% L
% Met:
0
8
16
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
8
0
47
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
16
8
0
0
0
0
0
0
0
8
8
0
0
% R
% Ser:
0
0
0
8
54
0
0
0
0
0
8
8
54
0
8
% S
% Thr:
0
8
0
8
0
0
31
8
8
54
8
0
0
0
8
% T
% Val:
16
0
0
0
0
8
0
16
8
8
54
0
0
0
0
% V
% Trp:
16
54
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
8
0
0
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _