KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPSR1
All Species:
11.21
Human Site:
S338
Identified Species:
20.56
UniProt:
Q6W5P4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6W5P4
NP_997055.1
371
42687
S338
C
V
F
S
S
S
I
S
F
P
C
R
E
Q
R
Chimpanzee
Pan troglodytes
XP_001168820
371
42711
S338
C
V
F
S
S
S
I
S
F
P
C
R
E
R
R
Rhesus Macaque
Macaca mulatta
Q56H79
371
42612
S338
C
V
F
S
S
S
I
S
F
P
C
G
E
R
R
Dog
Lupus familis
XP_539511
374
42921
C341
C
V
F
S
S
S
I
C
F
P
C
R
E
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BZP8
371
42420
C338
C
I
F
S
S
S
I
C
S
P
C
K
M
Q
R
Rat
Rattus norvegicus
P0C0L6
372
42620
C339
C
I
F
S
G
S
L
C
S
P
C
K
V
Q
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519137
132
15251
G99
G
K
R
Q
L
A
N
G
E
V
Q
C
W
A
L
Chicken
Gallus gallus
XP_426022
373
42686
C339
C
L
F
S
N
H
L
C
T
P
F
E
E
R
R
Frog
Xenopus laevis
P70031
453
51139
T364
M
P
I
F
V
A
N
T
W
K
A
F
D
E
L
Zebra Danio
Brachydanio rerio
XP_001341507
388
44497
D337
F
A
G
H
L
F
H
D
L
K
Q
N
L
F
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q868T3
506
55785
F413
C
L
F
S
S
Q
V
F
R
T
L
S
R
F
P
Honey Bee
Apis mellifera
XP_001122652
353
39441
T321
P
N
S
S
T
R
T
T
V
T
T
S
L
T
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784373
461
51252
P344
Q
L
W
N
V
W
H
P
S
S
A
P
F
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97
88.2
N.A.
89.2
88.9
N.A.
31
73.9
22.5
30.4
N.A.
31.6
35
N.A.
27.5
Protein Similarity:
100
99.4
98.6
93.8
N.A.
94.3
94.6
N.A.
34.5
86.3
40.4
50
N.A.
47.8
54.4
N.A.
45.1
P-Site Identity:
100
93.3
86.6
86.6
N.A.
66.6
53.3
N.A.
0
40
0
0
N.A.
26.6
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
73.3
N.A.
6.6
66.6
33.3
0
N.A.
40
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
16
0
0
0
0
16
0
0
8
8
% A
% Cys:
62
0
0
0
0
0
0
31
0
0
47
8
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
8
39
8
0
% E
% Phe:
8
0
62
8
0
8
0
8
31
0
8
8
8
16
0
% F
% Gly:
8
0
8
0
8
0
0
8
0
0
0
8
0
0
8
% G
% His:
0
0
0
8
0
8
16
0
0
0
0
0
0
8
0
% H
% Ile:
0
16
8
0
0
0
39
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
16
0
16
0
0
0
% K
% Leu:
0
24
0
0
16
0
16
0
8
0
8
0
16
0
16
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
8
8
0
16
0
0
0
0
8
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
8
0
54
0
8
0
0
8
% P
% Gln:
8
0
0
8
0
8
0
0
0
0
16
0
0
31
0
% Q
% Arg:
0
0
8
0
0
8
0
0
8
0
0
24
8
24
47
% R
% Ser:
0
0
8
70
47
47
0
24
24
8
0
16
0
0
0
% S
% Thr:
0
0
0
0
8
0
8
16
8
16
8
0
0
8
8
% T
% Val:
0
31
0
0
16
0
8
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
8
0
0
8
0
0
8
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _