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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
20
Human Site:
Y376
Identified Species:
36.67
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
Y376
L
Y
D
S
L
E
M
Y
N
P
S
D
S
G
P
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
Y376
L
Y
D
S
L
E
M
Y
N
P
S
D
S
G
P
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
Y375
L
Y
D
S
L
E
M
Y
N
P
S
D
S
G
P
Dog
Lupus familis
XP_540837
888
97890
P308
Y
N
P
S
D
S
G
P
E
M
E
E
T
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
Y374
L
Y
D
S
L
E
M
Y
N
P
S
D
S
G
P
Rat
Rattus norvegicus
O88588
961
104682
Y374
L
Y
D
S
L
E
M
Y
N
P
S
D
S
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_419325
859
94655
K279
E
S
V
H
S
T
P
K
P
T
L
R
R
F
F
Frog
Xenopus laevis
NP_001124414
878
97767
S298
D
I
E
N
P
S
D
S
G
P
E
M
E
D
D
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
S329
E
E
T
D
S
I
I
S
T
P
K
P
K
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
R510
T
A
G
N
S
E
R
R
S
S
D
K
S
D
Q
Honey Bee
Apis mellifera
XP_001120982
812
90475
Q232
K
I
P
T
N
A
R
Q
R
N
L
K
Q
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
L137
K
V
A
Q
V
T
V
L
G
L
S
S
Q
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
0
6.6
13.3
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
0
0
20
20
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
39
8
8
0
8
0
0
0
8
39
0
16
8
% D
% Glu:
16
8
8
0
0
47
0
0
8
0
16
8
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% F
% Gly:
0
0
8
0
0
0
8
0
16
0
0
0
0
39
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
16
0
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
16
0
0
0
0
0
0
8
0
0
8
16
8
8
0
% K
% Leu:
39
0
0
0
39
0
0
8
0
8
16
0
0
8
0
% L
% Met:
0
0
0
0
0
0
39
0
0
8
0
8
0
0
0
% M
% Asn:
0
8
0
16
8
0
0
0
39
8
0
0
0
0
0
% N
% Pro:
0
0
16
0
8
0
8
8
8
54
0
8
0
8
47
% P
% Gln:
0
0
0
8
0
0
0
8
0
0
0
0
16
0
8
% Q
% Arg:
0
0
0
0
0
0
16
8
8
0
0
8
8
0
0
% R
% Ser:
0
8
0
47
24
16
0
16
8
8
47
8
47
0
8
% S
% Thr:
8
0
8
8
0
16
0
0
8
8
0
0
8
0
0
% T
% Val:
0
8
8
0
8
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
39
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _