KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
22.73
Human Site:
Y200
Identified Species:
41.67
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
Y200
M
L
Q
R
R
K
R
Y
K
N
R
T
I
L
G
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
Y200
M
L
Q
R
R
K
R
Y
K
N
R
T
I
L
G
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
Y199
M
L
Q
R
R
K
R
Y
K
N
R
T
I
L
G
Dog
Lupus familis
XP_540837
888
97890
M147
L
I
N
M
A
E
V
M
Q
H
P
N
E
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
Y198
M
L
Q
R
R
K
R
Y
K
N
R
T
I
L
G
Rat
Rattus norvegicus
O88588
961
104682
Y198
M
L
Q
R
R
K
R
Y
K
N
R
T
I
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_419325
859
94655
L118
D
G
G
Q
L
L
S
L
H
S
N
M
K
D
V
Frog
Xenopus laevis
NP_001124414
878
97767
A137
A
V
G
S
I
N
M
A
E
V
M
Q
H
P
T
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
G168
T
E
G
A
Q
V
L
G
L
H
T
T
V
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
Y214
L
L
Q
R
R
K
K
Y
K
S
R
T
I
L
G
Honey Bee
Apis mellifera
XP_001120982
812
90475
R71
Q
S
S
K
R
T
L
R
S
N
E
M
A
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
0
0
6.6
N.A.
80
13.3
N.A.
0
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
0
13.3
13.3
26.6
N.A.
100
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
8
0
0
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
8
0
0
0
8
0
0
8
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
24
0
0
0
0
8
0
0
0
0
0
8
47
% G
% His:
0
0
0
0
0
0
0
0
8
16
0
0
8
0
0
% H
% Ile:
0
8
0
0
8
0
0
0
0
0
0
0
47
8
0
% I
% Lys:
0
0
0
8
0
47
8
0
47
0
0
0
8
8
0
% K
% Leu:
16
47
0
0
8
8
16
8
8
0
0
0
0
47
0
% L
% Met:
39
0
0
8
0
0
8
8
0
0
8
16
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
47
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
8
% P
% Gln:
8
0
47
8
8
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
47
54
0
39
8
0
0
47
0
0
0
0
% R
% Ser:
0
8
8
8
0
0
8
0
8
16
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
8
54
0
0
8
% T
% Val:
0
8
0
0
0
8
8
0
0
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _