KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
19.09
Human Site:
T124
Identified Species:
35
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
T124
V
P
R
L
F
S
L
T
L
K
K
L
V
M
L
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
T124
V
P
R
L
F
S
L
T
L
K
K
L
V
M
L
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
T123
L
T
R
L
F
S
L
T
L
K
K
L
V
M
L
Dog
Lupus familis
XP_540837
888
97890
I78
K
L
Q
G
S
K
R
I
L
R
S
N
E
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
T122
V
P
R
L
F
S
L
T
L
K
K
L
V
M
L
Rat
Rattus norvegicus
O88588
961
104682
T122
V
P
R
L
F
S
L
T
L
K
K
L
V
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_419325
859
94655
G49
E
Y
V
L
P
P
G
G
L
M
E
T
E
L
E
Frog
Xenopus laevis
NP_001124414
878
97767
S68
I
A
V
K
M
Q
G
S
K
R
I
L
R
S
H
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
A99
N
E
I
M
L
S
S
A
G
L
T
E
T
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
K124
A
V
K
M
Q
S
S
K
R
T
L
R
S
H
E
Honey Bee
Apis mellifera
XP_001120982
812
90475
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
86.6
6.6
N.A.
100
100
N.A.
0
13.3
6.6
13.3
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
93.3
33.3
N.A.
100
100
N.A.
0
26.6
26.6
20
N.A.
20
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
8
8
0
0
0
0
0
0
0
0
8
8
16
0
16
% E
% Phe:
0
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
16
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
8
0
8
0
0
0
0
8
0
0
8
0
0
8
8
% I
% Lys:
8
0
8
8
0
8
0
8
8
39
39
0
0
0
0
% K
% Leu:
8
8
0
47
8
0
39
0
54
8
8
47
0
8
47
% L
% Met:
0
0
0
16
8
0
0
0
0
8
0
0
0
39
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
31
0
0
8
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
39
0
0
0
8
0
8
16
0
8
8
0
0
% R
% Ser:
0
0
0
0
8
54
16
8
0
0
8
0
8
8
0
% S
% Thr:
0
8
0
0
0
0
0
39
0
8
8
8
8
0
0
% T
% Val:
31
8
16
0
0
0
0
0
0
0
0
0
39
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _