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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
20.61
Human Site:
S687
Identified Species:
37.78
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S687
Y
S
S
S
F
L
D
S
G
W
R
D
L
F
S
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S687
Y
S
S
S
F
L
D
S
G
W
R
D
L
F
S
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S686
Y
S
S
S
F
L
D
S
G
W
R
D
L
F
S
Dog
Lupus familis
XP_540837
888
97890
S619
S
G
W
R
D
L
F
S
R
S
E
P
P
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S685
Y
S
S
T
F
L
D
S
A
W
R
D
L
F
S
Rat
Rattus norvegicus
O88588
961
104682
S685
Y
S
S
T
F
L
D
S
A
W
R
D
L
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
G248
Q
Q
E
D
S
Q
E
G
E
L
S
T
L
D
V
Chicken
Gallus gallus
XP_419325
859
94655
P590
E
L
F
S
R
A
E
P
P
T
A
D
T
V
D
Frog
Xenopus laevis
NP_001124414
878
97767
L609
W
R
D
L
F
S
K
L
D
A
Q
T
T
V
E
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
S640
P
P
Q
T
D
S
F
S
A
D
I
V
D
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
G821
Q
A
Y
A
V
M
F
G
S
D
N
W
T
Q
L
Honey Bee
Apis mellifera
XP_001120982
812
90475
S543
T
L
S
K
Y
L
S
S
I
D
A
K
Y
S
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
K448
N
S
L
G
T
G
D
K
R
K
P
K
L
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
20
N.A.
86.6
86.6
N.A.
6.6
13.3
6.6
6.6
N.A.
0
20
N.A.
20
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
13.3
20
20
20
N.A.
20
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
0
0
24
8
16
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
16
0
47
0
8
24
0
47
8
8
8
% D
% Glu:
8
0
8
0
0
0
16
0
8
0
8
0
0
0
8
% E
% Phe:
0
0
8
0
47
0
24
0
0
0
0
0
0
39
0
% F
% Gly:
0
8
0
8
0
8
0
16
24
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
8
8
0
8
0
16
0
0
0
% K
% Leu:
0
16
8
8
0
54
0
8
0
8
0
0
54
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
8
0
0
0
0
0
8
8
0
8
8
8
8
0
% P
% Gln:
16
8
8
0
0
8
0
0
0
0
8
0
0
8
0
% Q
% Arg:
0
8
0
8
8
0
0
0
16
0
39
0
0
0
0
% R
% Ser:
8
47
47
31
8
16
8
62
8
8
8
0
0
8
47
% S
% Thr:
8
0
0
24
8
0
0
0
0
8
0
16
24
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
8
0
31
8
% V
% Trp:
8
0
8
0
0
0
0
0
0
39
0
8
0
0
0
% W
% Tyr:
39
0
8
0
8
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _