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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PACS1
All Species:
19.7
Human Site:
S393
Identified Species:
36.11
UniProt:
Q6VY07
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VY07
NP_060496.2
963
104898
S393
E
E
T
E
S
I
L
S
T
P
K
P
K
L
K
Chimpanzee
Pan troglodytes
XP_001170787
963
104910
S393
E
E
T
E
S
I
L
S
T
P
K
P
K
L
K
Rhesus Macaque
Macaca mulatta
XP_001111390
962
105061
S392
E
E
T
E
S
I
L
S
T
P
K
P
K
L
K
Dog
Lupus familis
XP_540837
888
97890
K325
S
T
P
K
P
K
L
K
P
F
F
E
G
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K212
961
104811
S391
E
E
T
E
S
I
L
S
T
P
K
P
K
L
K
Rat
Rattus norvegicus
O88588
961
104682
S391
E
E
T
E
S
I
L
S
T
P
K
P
K
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517191
517
58756
Chicken
Gallus gallus
XP_419325
859
94655
T296
V
S
H
S
G
S
Q
T
E
I
G
S
L
H
S
Frog
Xenopus laevis
NP_001124414
878
97767
K315
V
L
S
T
P
K
P
K
L
K
P
Y
F
E
G
Zebra Danio
Brachydanio rerio
NP_001092218
909
100535
S346
F
E
G
M
S
Q
S
S
S
Q
T
E
F
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524473
1175
124524
N527
N
S
S
Y
N
L
E
N
N
K
N
Q
K
C
I
Honey Bee
Apis mellifera
XP_001120982
812
90475
V249
L
L
K
R
R
F
R
V
S
E
D
L
D
Q
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796424
717
79113
D154
V
K
R
D
R
S
V
D
M
D
N
E
S
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
97
90.2
N.A.
97.6
97.6
N.A.
25.9
53.1
54.6
64
N.A.
28.3
36.1
N.A.
29.1
Protein Similarity:
100
99.9
97.6
91
N.A.
98.3
98.4
N.A.
36.5
66.1
69.1
77.9
N.A.
44.7
52.4
N.A.
45.1
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
0
0
0
20
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
0
6.6
6.6
26.6
N.A.
33.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
8
0
8
8
0
8
8
16
% D
% Glu:
39
47
0
39
0
0
8
0
8
8
0
24
0
8
0
% E
% Phe:
8
0
0
0
0
8
0
0
0
8
8
0
16
0
0
% F
% Gly:
0
0
8
0
8
0
0
0
0
0
8
0
8
8
8
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
39
0
0
0
8
0
0
0
0
8
% I
% Lys:
0
8
8
8
0
16
0
16
0
16
39
0
47
0
39
% K
% Leu:
8
16
0
0
0
8
47
0
8
0
0
8
8
39
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
8
0
0
8
8
0
16
0
0
0
0
% N
% Pro:
0
0
8
0
16
0
8
0
8
39
8
39
0
0
0
% P
% Gln:
0
0
0
0
0
8
8
0
0
8
0
8
0
8
0
% Q
% Arg:
0
0
8
8
16
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
8
16
16
8
47
16
8
47
16
0
0
8
8
0
24
% S
% Thr:
0
8
39
8
0
0
0
8
39
0
8
0
0
0
0
% T
% Val:
24
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _