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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TFAP2E
All Species:
18.18
Human Site:
S422
Identified Species:
50
UniProt:
Q6VUC0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6VUC0
NP_848643.2
442
46212
S422
G
L
D
K
M
F
L
S
S
V
G
S
G
H
G
Chimpanzee
Pan troglodytes
XP_524661
442
46222
S422
G
L
D
K
M
F
L
S
S
V
G
S
G
H
G
Rhesus Macaque
Macaca mulatta
XP_001106065
442
48233
N416
G
M
D
K
M
F
L
N
N
T
T
S
N
R
H
Dog
Lupus familis
XP_857355
431
47120
S409
A
M
D
K
M
Y
L
S
N
N
P
N
S
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q6VUP9
442
46265
S422
G
L
E
K
M
F
L
S
G
A
G
G
G
H
G
Rat
Rattus norvegicus
P58197
437
47928
S415
A
M
D
K
M
Y
L
S
N
N
P
N
S
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509668
442
48214
N416
G
M
D
K
V
F
L
N
N
N
T
T
N
R
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q2T9K2
434
47032
S413
G
M
D
K
I
F
M
S
S
T
G
N
G
H
S
Zebra Danio
Brachydanio rerio
Q6P0E7
423
45495
L404
L
L
E
A
L
K
L
L
D
K
G
E
N
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
67.1
62.2
N.A.
93.2
61
N.A.
66.7
N.A.
74.4
67.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
78
74.6
N.A.
95.9
73.3
N.A.
78
N.A.
83.9
78.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
46.6
40
N.A.
73.3
40
N.A.
33.3
N.A.
60
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
66.6
66.6
N.A.
80
66.6
N.A.
66.6
N.A.
86.6
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
78
0
0
0
0
0
12
0
0
0
0
0
0
% D
% Glu:
0
0
23
0
0
0
0
0
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% F
% Gly:
67
0
0
0
0
0
0
0
12
0
56
12
45
12
45
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
67
23
% H
% Ile:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
89
0
12
0
0
0
12
0
0
0
0
0
% K
% Leu:
12
45
0
0
12
0
89
12
0
0
0
0
0
0
0
% L
% Met:
0
56
0
0
67
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
23
45
34
0
34
34
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% R
% Ser:
0
0
0
0
0
0
0
67
34
0
0
34
23
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
23
23
12
0
0
23
% T
% Val:
0
0
0
0
12
0
0
0
0
23
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _