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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCHS2
All Species:
2.42
Human Site:
S580
Identified Species:
5.33
UniProt:
Q6V1P9
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6V1P9
NP_001136024.1
2916
322234
S580
V
I
E
K
R
E
H
S
P
S
W
T
F
E
H
Chimpanzee
Pan troglodytes
XP_526708
2852
314857
G549
Q
T
Q
A
H
P
L
G
P
Q
R
A
A
S
P
Rhesus Macaque
Macaca mulatta
XP_001100797
3386
356115
D799
V
L
R
V
R
A
H
D
P
D
Q
G
S
H
G
Dog
Lupus familis
XP_539776
2322
253044
L83
E
G
L
P
P
D
T
L
V
G
D
I
R
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q2PZL6
4981
540324
N1309
S
I
D
I
L
D
E
N
D
N
T
P
S
F
P
Rat
Rattus norvegicus
P58365
3317
365436
P666
V
F
D
E
N
D
N
P
P
T
F
S
K
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417264
2641
284628
V402
N
I
I
Y
L
I
C
V
D
Q
L
L
D
R
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001343759
3189
349215
Q765
V
N
I
L
Q
S
D
Q
P
P
A
L
F
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24292
3503
379762
S989
V
F
E
K
D
E
Y
S
V
N
V
S
E
S
R
Honey Bee
Apis mellifera
XP_392300
3377
363497
V852
V
E
L
N
V
E
D
V
N
D
N
G
P
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785445
3342
362092
P816
V
T
I
T
V
A
G
P
D
T
S
P
P
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
29.1
21.5
N.A.
21.1
25.4
N.A.
N.A.
23.4
N.A.
34.3
N.A.
27.4
25.4
N.A.
27.8
Protein Similarity:
100
97
45.4
38.2
N.A.
35
42.2
N.A.
N.A.
40.9
N.A.
52.2
N.A.
45
42.5
N.A.
46.5
P-Site Identity:
100
6.6
26.6
0
N.A.
6.6
13.3
N.A.
N.A.
6.6
N.A.
20
N.A.
33.3
13.3
N.A.
13.3
P-Site Similarity:
100
13.3
33.3
6.6
N.A.
33.3
60
N.A.
N.A.
6.6
N.A.
33.3
N.A.
53.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
19
0
0
0
0
10
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
10
28
19
10
28
19
10
0
10
0
0
% D
% Glu:
10
10
19
10
0
28
10
0
0
0
0
0
10
19
10
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
10
0
19
10
19
% F
% Gly:
0
10
0
0
0
0
10
10
0
10
0
19
0
0
19
% G
% His:
0
0
0
0
10
0
19
0
0
0
0
0
0
10
10
% H
% Ile:
0
28
28
10
0
10
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
0
19
0
0
0
0
0
0
0
0
10
0
10
% K
% Leu:
0
10
19
10
19
0
10
10
0
0
10
19
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
10
10
0
10
10
10
19
10
0
0
0
0
% N
% Pro:
0
0
0
10
10
10
0
19
46
10
0
19
19
10
19
% P
% Gln:
10
0
10
0
10
0
0
10
0
19
10
0
0
10
0
% Q
% Arg:
0
0
10
0
19
0
0
0
0
0
10
0
10
10
10
% R
% Ser:
10
0
0
0
0
10
0
19
0
10
10
19
19
19
0
% S
% Thr:
0
19
0
10
0
0
10
0
0
19
10
10
0
10
0
% T
% Val:
64
0
0
10
19
0
0
19
19
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _