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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCHS2 All Species: 6.97
Human Site: S2580 Identified Species: 15.33
UniProt: Q6V1P9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6V1P9 NP_001136024.1 2916 322234 S2580 Y E E K K T S S L D A D L R V
Chimpanzee Pan troglodytes XP_526708 2852 314857 S2516 Y E E K K T S S L D M D L R V
Rhesus Macaque Macaca mulatta XP_001100797 3386 356115 R3052 V L G L V R A R G R K A E A A
Dog Lupus familis XP_539776 2322 253044 N2014 N D P V W E Q N P F E I F L A
Cat Felis silvestris
Mouse Mus musculus Q2PZL6 4981 540324 S3655 S F H C S L T S G V T S L F S
Rat Rattus norvegicus P58365 3317 365436 I2984 L S N I T G A I V N T D D V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417264 2641 284628 S2333 A T D A G N A S A T V T V R V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001343759 3189 349215 P2876 K N A T K K T P S L S A N L N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24292 3503 379762 G3133 Y D E I P P F G A H A G S S G
Honey Bee Apis mellifera XP_392300 3377 363497 N3044 E S N A T A S N S Y V D P S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785445 3342 362092 M2979 K R S V A G S M S P R S Y D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 29.1 21.5 N.A. 21.1 25.4 N.A. N.A. 23.4 N.A. 34.3 N.A. 27.4 25.4 N.A. 27.8
Protein Similarity: 100 97 45.4 38.2 N.A. 35 42.2 N.A. N.A. 40.9 N.A. 52.2 N.A. 45 42.5 N.A. 46.5
P-Site Identity: 100 93.3 0 0 N.A. 13.3 6.6 N.A. N.A. 20 N.A. 6.6 N.A. 20 13.3 N.A. 13.3
P-Site Similarity: 100 93.3 6.6 13.3 N.A. 20 26.6 N.A. N.A. 40 N.A. 20 N.A. 26.6 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 19 10 10 28 0 19 0 19 19 0 10 28 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 10 0 0 0 0 0 0 19 0 37 10 10 0 % D
% Glu: 10 19 28 0 0 10 0 0 0 0 10 0 10 0 0 % E
% Phe: 0 10 0 0 0 0 10 0 0 10 0 0 10 10 0 % F
% Gly: 0 0 10 0 10 19 0 10 19 0 0 10 0 0 10 % G
% His: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 19 0 0 19 28 10 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 10 0 10 0 10 0 0 19 10 0 0 28 19 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 10 0 0 0 0 % M
% Asn: 10 10 19 0 0 10 0 19 0 10 0 0 10 0 10 % N
% Pro: 0 0 10 0 10 10 0 10 10 10 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % Q
% Arg: 0 10 0 0 0 10 0 10 0 10 10 0 0 28 0 % R
% Ser: 10 19 10 0 10 0 37 37 28 0 10 19 10 19 10 % S
% Thr: 0 10 0 10 19 19 19 0 0 10 19 10 0 0 0 % T
% Val: 10 0 0 19 10 0 0 0 10 10 19 0 10 10 37 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 28 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _