KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMC5
All Species:
0.3
Human Site:
S227
Identified Species:
0.74
UniProt:
Q6UXY8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXY8
NP_001098718.1
1006
114770
S227
F
G
E
P
D
Y
P
S
A
E
D
N
Q
N
L
Chimpanzee
Pan troglodytes
XP_001153396
949
108074
P218
D
I
Q
P
N
S
P
P
F
F
G
E
P
D
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547109
928
106078
P197
H
A
G
S
G
I
I
P
Y
V
D
V
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q32NZ6
967
111052
Y227
R
F
Y
G
K
P
D
Y
P
G
A
E
E
G
D
Rat
Rattus norvegicus
Q5M7W4
965
110699
A227
G
K
P
D
Y
P
G
A
E
E
G
D
V
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509198
962
110947
F229
S
V
P
Y
E
R
G
F
C
L
R
Y
C
G
K
Chicken
Gallus gallus
Q5YCC5
735
84359
Frog
Xenopus laevis
NP_001085652
725
84100
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395471
756
87723
F24
W
E
E
A
G
A
E
F
Y
Q
E
S
Y
P
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783735
885
99854
H154
R
Q
L
G
H
T
L
H
R
A
K
S
H
H
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.3
N.A.
72.4
N.A.
73.2
73.4
N.A.
50.8
20.5
26.7
N.A.
N.A.
N.A.
21.4
N.A.
24
Protein Similarity:
100
92.8
N.A.
78.3
N.A.
80
80.9
N.A.
63.4
37
43
N.A.
N.A.
N.A.
37.9
N.A.
39.9
P-Site Identity:
100
13.3
N.A.
6.6
N.A.
0
6.6
N.A.
0
0
0
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
33.3
N.A.
6.6
N.A.
6.6
20
N.A.
6.6
0
0
N.A.
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
10
0
10
10
10
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% C
% Asp:
10
0
0
10
10
0
10
0
0
0
20
10
0
10
10
% D
% Glu:
0
10
20
0
10
0
10
0
10
20
10
20
10
0
10
% E
% Phe:
10
10
0
0
0
0
0
20
10
10
0
0
0
0
0
% F
% Gly:
10
10
10
20
20
0
20
0
0
10
20
0
0
30
0
% G
% His:
10
0
0
0
10
0
0
10
0
0
0
0
10
10
10
% H
% Ile:
0
10
0
0
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
10
% K
% Leu:
0
0
10
0
0
0
10
0
0
10
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
20
20
0
20
20
20
10
0
0
0
10
10
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
20
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% R
% Ser:
10
0
0
10
0
10
0
10
0
0
0
20
0
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
0
10
10
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
10
10
10
0
10
20
0
0
10
10
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _