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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISLR2
All Species:
26.06
Human Site:
Y719
Identified Species:
63.7
UniProt:
Q6UXK2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UXK2
NP_001123609.1
745
78990
Y719
E
F
E
A
G
S
E
Y
S
D
R
L
P
L
G
Chimpanzee
Pan troglodytes
XP_001164572
428
46049
L408
A
E
G
V
P
G
Q
L
R
P
G
L
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001096467
746
79233
Y720
E
F
E
A
G
S
E
Y
S
D
R
L
P
L
G
Dog
Lupus familis
XP_544767
821
86588
Y795
E
F
E
A
G
S
E
Y
S
D
R
L
P
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5RKR3
745
79740
Y719
E
F
E
A
G
S
E
Y
S
D
R
L
P
L
G
Rat
Rattus norvegicus
XP_001074678
743
79457
X720
E
X
X
X
X
X
X
X
Q
A
D
S
G
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508596
722
77233
Y696
E
F
E
A
S
S
E
Y
S
D
R
L
P
L
G
Chicken
Gallus gallus
NP_001038132
699
77667
Y673
E
F
E
V
R
S
E
Y
S
D
K
L
P
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001013541
712
78510
Y687
E
F
E
V
G
S
E
Y
S
D
R
L
P
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q1ENI8
1285
146318
W1212
E
M
M
N
L
R
A
W
S
K
C
C
D
N
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.6
97.4
81.8
N.A.
89.5
85.6
N.A.
62.2
54.5
N.A.
49.2
N.A.
N.A.
N.A.
20.3
N.A.
Protein Similarity:
100
41.2
97.8
85
N.A.
92.6
89.1
N.A.
71.6
67.2
N.A.
63.8
N.A.
N.A.
N.A.
31.2
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
13.3
N.A.
93.3
80
N.A.
93.3
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
13.3
N.A.
93.3
86.6
N.A.
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
50
0
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
70
10
0
10
0
0
% D
% Glu:
90
10
70
0
0
0
70
0
0
0
0
0
0
0
0
% E
% Phe:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
50
10
0
0
0
0
10
0
10
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
10
0
0
0
80
10
90
10
% L
% Met:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
0
70
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
10
0
0
10
0
60
0
0
0
0
% R
% Ser:
0
0
0
0
10
70
0
0
80
0
0
10
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _