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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSSL1
All Species:
9.39
Human Site:
S215
Identified Species:
25.83
UniProt:
Q6UWY2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWY2
NP_999875.1
283
30334
S215
S
H
R
R
G
F
C
S
A
D
S
G
G
P
L
Chimpanzee
Pan troglodytes
XP_001146596
283
30282
S215
S
H
R
R
G
F
C
S
A
D
S
G
G
P
L
Rhesus Macaque
Macaca mulatta
XP_001117143
238
25779
A171
H
R
R
G
F
C
S
A
D
S
G
G
P
L
V
Dog
Lupus familis
XP_542217
536
56133
S462
R
R
R
R
G
F
C
S
A
D
S
G
G
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q14B24
284
30322
R216
T
H
S
G
D
R
R
R
R
G
F
C
S
A
D
Rat
Rattus norvegicus
Q6IE59
278
29499
R210
T
H
S
G
D
R
R
R
R
G
F
C
S
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989788
260
28466
A193
I
T
D
N
M
I
C
A
G
S
K
R
G
D
K
Frog
Xenopus laevis
Q63ZK0
263
29212
C196
E
I
T
P
N
M
I
C
A
I
E
A
K
K
D
Zebra Danio
Brachydanio rerio
XP_002666316
269
29684
Y195
G
H
G
G
S
C
R
Y
D
S
G
G
P
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
69.2
41.7
N.A.
69
71.3
N.A.
N.A.
36.4
30.3
34.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.2
74.1
44.4
N.A.
74.3
77.7
N.A.
N.A.
51.2
45.9
52.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
86.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
86.6
N.A.
13.3
13.3
N.A.
N.A.
20
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
23
45
0
0
12
0
23
0
% A
% Cys:
0
0
0
0
0
23
45
12
0
0
0
23
0
0
0
% C
% Asp:
0
0
12
0
23
0
0
0
23
34
0
0
0
12
34
% D
% Glu:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
0
0
12
34
0
0
0
0
23
0
0
0
0
% F
% Gly:
12
0
12
45
34
0
0
0
12
23
23
56
45
0
0
% G
% His:
12
56
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
12
0
0
0
12
12
0
0
12
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
0
12
12
12
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
34
% L
% Met:
0
0
0
0
12
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
23
34
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
23
45
34
0
23
34
23
23
0
0
12
0
0
0
% R
% Ser:
23
0
23
0
12
0
12
34
0
34
34
0
23
0
0
% S
% Thr:
23
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _