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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCLAT1 All Species: 6.36
Human Site: Y139 Identified Species: 10
UniProt: Q6UWP7 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6UWP7 NP_001002257.1 414 48920 Y139 L W N C L M R Y S Y L R L E K
Chimpanzee Pan troglodytes XP_001163263 414 48844 Y139 L W N C L M R Y S Y L R L E K
Rhesus Macaque Macaca mulatta XP_001104425 376 44573 A127 G F G W A M Q A A A Y I F I H
Dog Lupus familis XP_540138 376 44590 A127 G F G W A M Q A A A Y I F I H
Cat Felis silvestris
Mouse Mus musculus Q3UN02 376 44381 V127 G F G W A M Q V A A F I F I H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510123 376 44599 A127 G F G W A M Q A A A Y I F I H
Chicken Gallus gallus Q5F3X0 378 44430 A129 G W A M Q V A A F I F I Q R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NYV8 388 44727 D139 F I Q R R W E D D R T H M S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001123248 373 43793 N124 M Y Q A C L P N V A T H R L K
Nematode Worm Caenorhab. elegans NP_504643 344 40052 W95 R L D W L F S W N A L Y K M D
Sea Urchin Strong. purpuratus XP_782691 375 43561 S126 N A P C I G W S M Q V A C F I
Poplar Tree Populus trichocarpa XP_002327077 372 42900 K123 L W N L A L R K G C L G Y I K
Maize Zea mays Q41745 374 42553 L125 M K K S S K F L P V I G W S M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L4Y2 378 43045 Y129 G C L G Y I K Y V L K S S L M
Baker's Yeast Sacchar. cerevisiae Q12185 396 45920 V139 V S N L G G N V Y I I L K K A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 88.8 84.5 N.A. 80.9 N.A. N.A. 73.4 69.3 N.A. 57.2 N.A. N.A. 34.5 34 35.2
Protein Similarity: 100 99.7 89.8 88.1 N.A. 85.9 N.A. N.A. 82.6 80.1 N.A. 71.9 N.A. N.A. 55 52.1 52.9
P-Site Identity: 100 100 6.6 6.6 N.A. 6.6 N.A. N.A. 6.6 13.3 N.A. 0 N.A. N.A. 6.6 13.3 6.6
P-Site Similarity: 100 100 26.6 26.6 N.A. 26.6 N.A. N.A. 26.6 20 N.A. 6.6 N.A. N.A. 26.6 33.3 20
Percent
Protein Identity: 28.2 24.4 N.A. 28 20.7 N.A.
Protein Similarity: 44.9 39.8 N.A. 45.1 34.7 N.A.
P-Site Identity: 40 0 N.A. 6.6 6.6 N.A.
P-Site Similarity: 46.6 13.3 N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 34 0 7 27 27 40 0 7 0 0 7 % A
% Cys: 0 7 0 20 7 0 0 0 0 7 0 0 7 0 0 % C
% Asp: 0 0 7 0 0 0 0 7 7 0 0 0 0 0 7 % D
% Glu: 0 0 0 0 0 0 7 0 0 0 0 0 0 14 0 % E
% Phe: 7 27 0 0 0 7 7 0 7 0 14 0 27 7 0 % F
% Gly: 40 0 27 7 7 14 0 0 7 0 0 14 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 14 0 0 27 % H
% Ile: 0 7 0 0 7 7 0 0 0 14 14 34 0 34 7 % I
% Lys: 0 7 7 0 0 7 7 7 0 0 7 0 14 7 34 % K
% Leu: 20 7 7 14 20 14 0 7 0 7 27 7 14 14 0 % L
% Met: 14 0 0 7 0 40 0 0 7 0 0 0 7 7 14 % M
% Asn: 7 0 27 0 0 0 7 7 7 0 0 0 0 0 7 % N
% Pro: 0 0 7 0 0 0 7 0 7 0 0 0 0 0 0 % P
% Gln: 0 0 14 0 7 0 27 0 0 7 0 0 7 0 0 % Q
% Arg: 7 0 0 7 7 0 20 0 0 7 0 14 7 7 0 % R
% Ser: 0 7 0 7 7 0 7 7 14 0 0 7 7 14 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 14 0 0 0 0 % T
% Val: 7 0 0 0 0 7 0 14 14 7 7 0 0 0 0 % V
% Trp: 0 27 0 34 0 7 7 7 0 0 0 0 7 0 0 % W
% Tyr: 0 7 0 0 7 0 0 20 7 14 20 7 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _